NDC1 Antibody, HRP conjugated
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中文名稱：NDC1兔多克隆抗體, HRP偶聯(lián)
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貨號：CSB-PA874808LB01HU
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規(guī)格：￥880
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) NDC1 Polyclonal antibody
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Uniprot No.：
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基因名：NDC1
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別名：NDC1; TMEM48; Nucleoporin NDC1; hNDC1; Transmembrane protein 48
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Recombinant Human Nucleoporin NDC1 protein (385-517AA)
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：HRP
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. Required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane.
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基因功能參考文獻(xiàn)：
- miR-421 can suppress TMEM48 so that leads the non-small cancer cell lines (A549) to apoptosis. PMID: 29906465
- In mature human spermatozoa, SEPT12 and NDC1 are majorly colocalized in the centrosome regions; however, NDC1 is only slightly co-expressed with SEPT12 at the annulus of the sperm tail. PMID: 27854341
- The biological relevance of TMEM48 in NSCLC progression. PMID: 26392108
- Human homologue NDC1/NET3 contains three FG repeats in the C-terminus, a feature of many nuclear pore proteins. PMID: 16779818
- NDC1-mediated localization of ALADIN to nuclear pore complexes is essential for selective nuclear protein import; abrogation of the interaction between ALADIN and NDC1 may be important for the development of triple-A syndrome. PMID: 19703420
- ALADIN is anchored in the nuclear envelope via NDC1 and that this interaction gets lost, if ALADIN is mutated. PMID: 19782045
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亞細(xì)胞定位：Nucleus, nuclear pore complex. Nucleus membrane; Multi-pass membrane protein. Note=Central core structure of the nuclear pore complex.
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蛋白家族：NDC1 family
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數(shù)據(jù)庫鏈接：
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