NCE102 Antibody

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說明書

中文名稱：

NCE102兔多克隆抗體
貨號：

CSB-PA614189XA01SVG
規格：

￥440
圖片：
Western Blot
Positive WB detected in Recombinant protein
All lanes: NCE102 antibody at 1:2000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 20.1 kDa
Observed band size: 22 kDa
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

Uniprot No.：

Q12207
基因名：

NCE102
別名：

Non-classical export protein 2 NCE102 NCE2 RTG2S2 YPR149W P9659.2
反應種屬：

Human coronavirus 229E
免疫原：

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) NCE2 protein
免疫原種屬：

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
標記方式：

Non-conjugated
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Protein G
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Involved in membrane organization. Required for the formation of membrane compartments of CAN1 (MCCs), localization of CAN1 at the MCCs and subsequent invagination of the plasma membrane at the MCCs sites. Involved in eisosome organization and might act as a sensor of sphingolipids that regulates plasma membrane function. Involved in a novel pathway of export of proteins that lack a cleavable signal sequence. It may be an accessory subunit to an essential core component of the non-classical export machinery. Non-classical export pathway functions also as an alternative clearance/detoxification pathway to eliminate damaged material, when the basic repair pathway is not sufficient.
基因功能參考文獻：
1. Attenuation of the endocytic pathway through deletion of the gene END3 impaired the Nce102-mediated rescue, suggesting that the Nce102 mutants lead to suppression through the yeast endocytic pathway. PMID: 27317660
2. Overexpression of NCE102 in wild type yeast strain BY4742 neither protected against oxidative stress due to diethylmaleate nor extended yeast lifespan compared to its parental wild type strain. PMID: 17415679
3. Results suggest that Nce102 might act as a sensor of sphingolipids that regulates plasma membrane function. PMID: 19564405
亞細胞定位：

Cell membrane; Multi-pass membrane protein. Note=Associates with the ergosterol-rich membrane compartment of CAN1 (MCC). Accumulates in membrane domains at eisosomes.
蛋白家族：

NCE102 family
數據庫鏈接：

KEGG: sce:YPR149W

STRING: 4932.YPR149W

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