Mybpc3 Antibody

Name: Mybpc3 Antibody
Brand: CUSABIO
SKU: CSB-PA015267YA01RA

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說明書

產品詳情

產品名稱：

Rabbit anti-Rattus norvegicus (Rat) Mybpc3 Polyclonal antibody
Uniprot No.：

P56741
基因名：

Mybpc3
別名：

Mybpc3 antibody; Myosin-binding protein C antibody; cardiac-type antibody; Cardiac MyBP-C antibody; C-protein antibody; cardiac muscle isoform antibody
宿主：

Rabbit
反應種屬：

Rat
免疫原：

Recombinant Rat Myosin-binding protein C, cardiac-type protein (645-864AA)
免疫原種屬：

Rattus norvegicus (Rat)

標記方式：

Non-conjugated

本頁面中的產品，Mybpc3 Antibody (CSB-PA015267YA01RA)，的標記方式是Non-conjugated。對于Mybpc3 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA015267YB01RA	Mybpc3 Antibody, HRP conjugated	ELISA
FITC	CSB-PA015267YC01RA	Mybpc3 Antibody, FITC conjugated
Biotin	CSB-PA015267YD01RA	Mybpc3 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role.
基因功能參考文獻：
1. Data show that expression of mutant protein cMyBP-C (cMyBP-C(C10mut)) in cultured adult rat cardiomyocytes led to improper localization and contractile dysfunction. PMID: 25583989
2. These results show that the N-terminal region of MyBP-C stabilizes the ON state of thin filaments and the OFF state of thick filaments and lead to a novel hypothesis for the physiological role of MyBP-C in the regulation of cardiac contractility. PMID: 25512492
3. Expression of an actin binding-deficient cMyBP-C resulted in abnormal cytosolic distribution of the protein, indicating that interaction with actin is essential for the formation and/or maintenance of normal cMyBP-C sarcomeric distribution. PMID: 22982234
4. N' region of cMyBP-C is toxic to cardiomyocytes and able to induce cell death. PMID: 22527638
5. this study suggests that cMyBP-C is an easily releasable myofilament protein that is dephosphorylated, degraded and released into the circulation post-MI. PMID: 21971072
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蛋白家族：

Immunoglobulin superfamily, MyBP family
數據庫鏈接：

KEGG: rno:295929

STRING: 10116.ENSRNOP00000016652

UniGene: Rn.162668

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