Ms4a1 Antibody, HRP conjugated
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中文名稱：Ms4a1兔多克隆抗體, HRP偶聯
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貨號：CSB-PA015007LB01MO
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Mus musculus (Mouse) Ms4a1 Polyclonal antibody
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Uniprot No.：
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基因名：
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別名：Ms4a1 antibody; Cd20 antibody; Ly-44 antibody; Ms4a2 antibody; B-lymphocyte antigen CD20 antibody; B-cell differentiation antigen Ly-44 antibody; Lymphocyte antigen 44 antibody; Membrane-spanning 4-domains subfamily A member 1 antibody; CD antigen CD20 antibody
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宿主：Rabbit
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反應種屬：Mouse
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免疫原：Recombinant Mouse B-lymphocyte antigen CD20 protein (111-291AA)
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免疫原種屬：Mus musculus (Mouse)
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標記方式：HRP
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR.
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基因功能參考文獻：
- Our findings indicate that anti-CD20-IFNalpha eradicates B-cell lymphoma by employing tumor cells as antigen-presenting cells to reactivate tumor-infiltrating CD8(+) T cells and synergizing with anti-PD-L1 treatment PMID: 28533311
- Galectin-1 has a role in driving lymphoma CD20 immunotherapy resistance in a mouse model PMID: 26888257
- Results indicate that an antigen-specific B cell response towards intracellular pathogens can be generated during anti-CD20 depletion therapy. PMID: 26261496
- this study demonstrates a role for CD20 in B cell activation and T-dependent humoral immunity. PMID: 23966626
- CD20 is required for store-operated calcium entry in C2C12 myoblasts. PMID: 22982241
- immunization of mice with the CD20 extracellular domain-6 using Freund's or QS-21 adjuvants was shown to exert significant biological effects in vivo with the pronounced depletion of splenic B cells. PMID: 20189250
- type I CD20 antibody cytotoxicity critically depends on Fc receptor ITAM signaling PMID: 20354182
- CD20 deficiency in humans results in impaired T cell-independent antibody responses. PMID: 20038800
- review of structure, function, tissue and cell distribution PMID: 12144126
- Anti-CD20 antibodies rapidly depleted the vast majority of circulating and tissue B cells in an isotype-restricted manner dependent on effector cell Fc receptor expression. PMID: 15210744
- expression in bacterial cells; isolation and biophysical and structural studies PMID: 16285718
- In mice treated with anti-CD20 mAb, development of arthritis was significantly reduced in comparison to control mAb-treated mice PMID: 18354225
- involvement of CD20 in calcium influx PMID: 18474602
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亞細胞定位：Cell membrane; Multi-pass membrane protein. Cell membrane; Lipid-anchor.
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蛋白家族：MS4A family
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數據庫鏈接：
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