Mmp7 Antibody

^{Rare Species}

中文名稱：

Mmp7兔多克隆抗體
貨號：

CSB-PA014677EA01RA
規格：

￥440
圖片：
Western blot
All lanes: Mmp7 antibody at 2µg/ml
Lane 1: Colo320 whole cell lysaye
Lane 2: NIH/3T3 whole cell lysaye
Lane 3: Mouse lung tissue
Lane 4: HepG2 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 30 kDa
Observed band size: 30 kDa
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

產品名稱：

Rabbit anti-Rattus norvegicus (Rat) Mmp7 Polyclonal antibody
Uniprot No.：

P50280
基因名：

Mmp7
別名：

Mmp7 antibody; Mmp-7Matrilysin antibody; EC 3.4.24.23 antibody; Matrin antibody; Matrix metalloproteinase-7 antibody; MMP-7 antibody; Pump-1 protease antibody; Uterine metalloproteinase antibody
宿主：

Rabbit
反應種屬：

Rat, Mouse, Human
免疫原：

Recombinant Rat Matrilysin protein (98-267AA)
免疫原種屬：

Rattus norvegicus (Rat)

標記方式：

Non-conjugated

本頁面中的產品，Mmp7 Antibody (CSB-PA014677EA01RA)，的標記方式是Non-conjugated。對于Mmp7 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA014677EB01RA	Mmp7 Antibody, HRP conjugated	ELISA
FITC	CSB-PA014677EC01RA	Mmp7 Antibody, FITC conjugated
Biotin	CSB-PA014677ED01RA	Mmp7 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, WB

推薦稀釋比：

Application	Recommended Dilution
WB	1:1000-1:5000

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase.
基因功能參考文獻：
1. Placental ischemia, possibly through the release of TNF-alpha, causes increases in the levels of matrix metalloproteinase (MMP)-1 and MMP-7, which could alter collagen deposition and cause inadequate uteroplacental and vascular remodeling in hypertension in pregnancy. PMID: 28626073
2. Expression of MMP-7, c-Jun and c-Fos were increased in skin photoaging. PMID: 23870463
3. Increased extracellular nerve growth factor precursor levels following seizures are stabilized by altered MMP-7 enzymatic activity, leading to increased neuronal death via activation of p75(NTR). PMID: 22238106
4. MMP-7 significantly contributes to intestinal epithelial wound closure. IL-1beta increased MMP-7 levels beyond those seen during normal healing. PMID: 20655064
5. important role of MMP-2, MMP-9, and TIMP-4 in hypertensive remodeling of the cortex and medulla in the SHR rat PMID: 12923405
6. Adrenergic alpha-agonist-induced activation of matrix metalloproteinase-7 promotes vasoconstriction through the epidermal growth factor-receptor pathway. PMID: 14656925
7. MMP-7, which was produced by osteoclasts at the tumor-bone interface, was capable of processing RANKL to a soluble form that promoted osteoclast activation. PMID: 15894268
8. Diminished expression of MMP-7 may play a role in fibronectin accumulation in the diabetic kidney in response to advanced glycation end products and/or TGF-beta. PMID: 17554258
9. Claudin-7, kidney injury molecule-1 (Kim-1), and matrix metalloproteinase-7 (MMP-7) changed by aging and changes attenuated by caloric restriction. PMID: 17670906
10. These results suggest a novel role for noncanonical WNT signaling in maintaining kidney transplant tolerance with MMP7 being a key target. PMID: 18209025
11. MMP-7 cleaves the NR1 subunit of the N-methyl-d-aspartate (NMDA) receptor to generate an N-terminal fragment of approximately 65 kDa PMID: 18644839
12. Agonist signaling of both hypertension and hypertrophy depends on posttranscriptional and transcriptional mechanisms that involve MMP-7, which is transcriptionally connected with ADAM-12 PMID: 19398663
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亞細胞定位：

Secreted, extracellular space, extracellular matrix.
蛋白家族：

Peptidase M10A family
數據庫鏈接：

KEGG: rno:25335

STRING: 10116.ENSRNOP00000014041

UniGene: Rn.10282

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