MYOZ1 Antibody
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中文名稱：MYOZ1兔多克隆抗體
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貨號：CSB-PA904228
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規格：￥1100
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圖片：
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The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using CSB-PA904228(MYOZ1 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200) -
Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane: Mouse muscle tissue, Primary antibody: CSB-PA904228(MYOZ1 Antibody) at dilution 1/1000, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
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其他：
產品詳情
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Uniprot No.：
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基因名：MYOZ1
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別名：actinin- and telethonin-binding protein antibody; Calsarcin 2 antibody; Calsarcin-2 antibody; CS 2 antibody; FATZ antibody; Filamin, actinin and telethonin binding protein antibody; Filamin- antibody; MYOZ antibody; MYOZ1 antibody; MYOZ1_HUMAN antibody; Myozenin-1 antibody; Protein FATZ antibody
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宿主：Rabbit
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反應種屬：Human,Mouse
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免疫原：Fusion protein of Human MYOZ1
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：Antigen affinity purification
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產品提供形式：Liquid
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應用范圍：ELISA,WB,IHC
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推薦稀釋比：
Application Recommended Dilution ELISA 1:2000-1:5000 WB 1:500-1:2000 IHC 1:50-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Myozenins may serve as intracellular binding proteins involved in linking Z-disk proteins such as alpha-actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis.
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基因功能參考文獻：
- Our results implicate MYOZ1 as the causative gene at the chromosome 10q22 locus for AF. PMID: 24177373
- Our findings provide evidence for a novel connection between the Z-disc protein calsarcin-2 and the sarcolemma via filamins and beta1 integrins. PMID: 16076904
- Mutations in PDLIM3 and MYOZ1, encoding myocyte Z line proteins, do not play any significant role in the genetic etiology of idiopathic DCM. PMID: 17254821
- A large number of variations were found in many of the genes (myozenin 1, gamma-filamin, kinectin-1) in patients with limb-girdle muscular dystrophies and controls. PMID: 19472918
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亞細胞定位：Nucleus. Cell projection, pseudopodium. Note=Localized to the nucleus and pseudopodia of undifferentiated cells and detected throughout the myotubes of differentiated cells. Colocalizes with ACTN2, FLNC and MYOT at the Z-lines of skeletal muscle.
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蛋白家族：Myozenin family
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組織特異性：Expressed primarily in skeletal muscle. Detected at lower levels in heart, prostate and pancreas.
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數據庫鏈接：
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