MYBPH Antibody, Biotin conjugated
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中文名稱：MYBPH兔多克隆抗體, Biotin偶聯
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貨號：CSB-PA618765LD01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) MYBPH Polyclonal antibody
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Uniprot No.：
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基因名：MYBPH
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別名：bHLHe38 antibody; H protein antibody; H-protein antibody; l-myc protein antibody; l-myc-1 proto-oncogene antibody; LMYC antibody; MyBP H antibody; MyBP-H antibody; Mybph antibody; MYBPH_HUMAN antibody; myc-related gene from lung cancer antibody; MYCL antibody; Myosin binding protein H antibody; Myosin binding protein, 86-KD antibody; Myosin-binding protein H antibody; Oncogene lmyc antibody; V-myc avian myelocytomatosis viral oncogene homolog 1, lung carcinoma derived antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Myosin-binding protein H protein (3-159AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Biotin
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Binds to myosin; probably involved in interaction with thick myofilaments in the A-band.
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基因功能參考文獻：
- variation in MYBPH can modulate the severity of hypertrophy in hypertrophic cardiomyopathy patients. PMID: 26969327
- MyBP-H expression signals the onset of dysregulation in actin-myosin interaction; this in turn might contribute to the pathogenesis of amyotrophic lateral sclerosis. PMID: 24184715
- These results suggest that MYBPH inhibits RLC and NMHC IIA, independent components of NM IIA, and negatively regulates actomyosin organization at 2 distinct steps, resulting in firm inhibition of NM IIA assembly. PMID: 23068101
- MYBPH inhibited assembly competence-conferring phosphorylation of the myosin regulatory light chain (RLC) as well as activating phosphorylation of LIM domain kinase, unexpectedly through its direct physical interaction with Rho kinase 1 PMID: 22085929
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蛋白家族：Immunoglobulin superfamily, MyBP family
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組織特異性：Mainly expressed in the skeletal muscle. Slightly expressed in the left atrium and arteria mammaria interna.
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數據庫鏈接：
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