MUC15 Antibody
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中文名稱(chēng)：MUC15兔多克隆抗體
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貨號(hào)：CSB-PA113113
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規(guī)格：￥1100
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圖片：
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The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA113113(MUC15 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200) -
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA113113(MUC15 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：MUC15
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別名：Component II antibody; Glycoprotein 4 antibody; Glycoprotein C antibody; MUC 15 antibody; MUC-15 antibody; Muc15 antibody; MUC15_HUMAN antibody; Mucin 15 antibody; Mucin 15 cell surface associated antibody; Mucin-15 antibody; PAS3 antibody; PASIII antibody
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Fusion protein of Human MUC15
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：Antigen affinity purification
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA,IHC
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推薦稀釋比：
Application Recommended Dilution ELISA 1:2000-1:5000 IHC 1:25-1:100 -
Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：May play a role in the cell adhesion to the extracellular matrix.
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基因功能參考文獻(xiàn)：
- Frameshift mutations of MUC15 gene is associated with gastric and colorectal cancers. PMID: 25573589
- Multivariate analysis suggested that MUC15 overexpression was an independent factor for prognosis (hazard risk: 3.216; P=0.009). It was concluded that MUC15 is overexpressed in glioma tissues. PMID: 24710941
- MUC15 inhibits dimerization of EGFR and PI3K-AKT signaling and is associated with aggressive hepatocellular carcinomas in patients. PMID: 23933603
- MUC15 is a strong candidate for eczema. PMID: 22657408
- MUC4 and MUC15 were overexpressed in papillary thyroid carcinoma, and high MUC15 expression was associated with high malignant potential. PMID: 21615302
- MUC15 was expressed most highly in human placenta. MUC15 mRNA & protein increased with gestational age (P < 0.05, 1st versus 3rd trimester). Differential expression of MUC15 in human placentas may play critical role in regulation of trophoblast invasion. PMID: 17720698
- Overexpression of MUC15 activates extracellular signal-regulated kinase 1/2 and promotes the oncogenic potential of colon cancer cells. PMID: 19520792
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亞細(xì)胞定位：[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.
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組織特異性：Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon, peripheral blood leukocyte, bone marrow, lymph node and lung.
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數(shù)據(jù)庫(kù)鏈接：
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