MT1F Antibody, Biotin conjugated
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中文名稱：MT1F兔多克隆抗體, Biotin偶聯
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貨號：CSB-PA17409D0Rb
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) MT1F Polyclonal antibody
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Uniprot No.：
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基因名：MT1F
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別名：MT1F antibody; PRO0376 antibody; Metallothionein-1F antibody; MT-1F antibody; Metallothionein-IF antibody; MT-IF antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Metallothionein-1F protein (1-61AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Biotin
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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靶點詳情
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功能：Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.
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基因功能參考文獻：
- we found that metallothionein expression induced by Cd occurred much later, with the expression seen at least 12h or more after the Nrf2-dependent immediate responses were almost completed. PMID: 24440467
- Metallothionein may have a role in the control of apoptosis in pleomorphic adenoma. PMID: 23332881
- Aortic protection in diabetes by zinc supplementation is associated with upregulation of both metallothionein and Nrf2 expression. PMID: 23536959
- findings show 5 MT isoforms were overexpressed in non-small cell lung cancer and overexpression of MT-1F and MT-2A predicted poor outcome; both isoforms may be involved in progression of this cancer type; upregulated MT-1F expression associated with larger primary tumor size and higher grade of malignanacy PMID: 23064051
- MT1F is a putative tumor suppressor gene in colon carcinogenesis that is downregulated mainly by loss of heterozygosity in colon cancer tissue PMID: 22426038
- This study identifies for the first time the relevant metallothionein isoforms for colorectal cancer progression. PMID: 21820154
- Studies provide the mechanistic properties of metal binding for metallothionein metallation. PMID: 21409206
- MT-1 rs8052394 A allele is associated with oral squamous cell carcinoma. PMID: 21128001
- In the liver cancer tissue, MT1F shows down-regulated expression that supports the inhibited function of MT1F in cancer growth PMID: 15369632
- Knockdown of MT1F gene increased particular matter(2.5)-induced H2O2 release in alveolar macrophages. PMID: 19251948
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蛋白家族：Metallothionein superfamily, Type 1 family
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數據庫鏈接：
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