MSTO1 Antibody, HRP conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) MSTO1 Polyclonal antibody
Uniprot No.：

Q9BUK6
基因名：

MSTO1
別名：

MSTO1 antibody; LST005 antibody; SLTP005 antibody; Protein misato homolog 1 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Protein misato homolog 1 protein (1-280AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

HRP
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Involved in the regulation of mitochondrial distribution and morphology. Required for mitochondrial fusion and mitochondrial network formation.
基因功能參考文獻：
1. we have described two unrelated patients with biallelic MSTO1 mutations. Our report provides valuable information on the consequences of MSTO1 mutations for human phenotypes. PMID: 29339779
2. Recessive mutations in MSTO1 cause mitochondrial dynamics impairment, leading to myopathy and ataxia PMID: 28544275
3. Thus, an MSTO1 loss-of-function mutation is associated with a human disorder showing mitochondrial involvement. MSTO1 likely has a physiologically relevant role in mitochondrial morphogenesis by supporting mitochondrial fusion. PMID: 28554942
4. These results indicated that human Misato has a role(s) in mitochondrial distribution and morphology and that its unregulated expression leads to cell death. PMID: 17349998
相關疾病：

Myopathy, mitochondrial, and ataxia (MMYAT)
亞細胞定位：

Mitochondrion outer membrane. Cytoplasm.
蛋白家族：

Misato family
組織特異性：

Present in all cell lines tested (at protein level). Widely expressed.
數據庫鏈接：

HGNC: 29678

OMIM: 617619

KEGG: hsa:55154

UniGene: Hs.656547

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