MRPS30 Antibody

說明書

產品詳情

Uniprot No.：

Q9NP92
基因名：

MRPS30
別名：

28S ribosomal protein S30 antibody; 28S ribosomal protein S30; mitochondrial antibody; Mitochondrial 28S ribosomal protein S30 antibody; mitochondrial antibody; Mitochondrial ribosomal protein S30 antibody; MRP S30 antibody; MRP-S30 antibody; MRPS30 antibody; PAP antibody; PDCD9 antibody; Programmed cell death 9 antibody; Programmed cell death protein 9 antibody; RT30_HUMAN antibody; S30mt antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Synthesized peptide derived from the C-terminal region of Human MRP-S30.
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
產品提供形式：

Liquid
應用范圍：

WB, ELISA

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:2000
ELISA	1:10000

Protocols：

Western Blotting (WB) Protocol
ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

基因功能參考文獻：
1. data suggest that the strongest signal of association at 5p12 is mediated through coordinated activation of FGF10 and MRPS30, two candidate genes for breast cancer pathogenesis PMID: 27640304
2. Among the 10 SNPs studied, rs10941679 in MRPS30 showed significant association with breast cancer risk when differences between the case and control groups in this Han Chinese population were compared. PMID: 24528085
3. data suggest the 5p12 risk allele affects MRPS30 expression in estrogen-responsive tumor cells after tumor initiation by a mechanism affecting chromatin availability. PMID: 24388359
4. The risk-associated allele of rs7716600 in the 5p12 ER-positive susceptibility locus was associated with elevated expression of the nearby gene MRPS30 and decreased MRPS30 promoter methylation exclusively in ER-positive tumors. eQTL and in vitro experiments suggest this allele affects MRPS30 expression in estrogen-responsive tumor cells after tumor initiation by a mechanism affecting chromatin availability. PMID: 24388359
亞細胞定位：

Mitochondrion.
蛋白家族：

Mitochondrion-specific ribosomal protein mL65 family
組織特異性：

Heart, skeletal muscle, kidney and liver. Lower expression in placenta and peripheral blood leukocytes.
數據庫鏈接：

HGNC: 8769

OMIM: 611991

KEGG: hsa:10884

STRING: 9606.ENSP00000424328

UniGene: Hs.124165

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