MMP25 Antibody
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中文名稱：MMP25兔多克隆抗體
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貨號：CSB-PA198245
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規格：￥1100
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圖片：
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The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA198245(MMP25 Antibody) at dilution 1/80, on the right is treated with synthetic peptide. (Original magnification: ×200)
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其他：
產品詳情
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Uniprot No.：
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基因名：MMP25
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別名：Leukolysin antibody; matrix metallopeptidase 25 antibody; matrix metallopeptidase like 1 antibody; matrix metalloproteinase 20 antibody; Matrix Metalloproteinase 25 antibody; Matrix metalloproteinase 25 precursor antibody; Matrix metalloproteinase-25 antibody; Membrane type 6 Matrix Metalloproteinase antibody; Membrane type Matrix Metalloproteinase 6 antibody; Membrane-type matrix metalloproteinase 6 antibody; Membrane-type-6 matrix metalloproteinase antibody; MMP 25 antibody; MMP-25 antibody; MMP20 antibody; MMP20A antibody; MMP25 antibody; MMP25_HUMAN antibody; MMPL1 antibody; MT MMP 6 antibody; MT-MMP 6 antibody; MT6 MMP antibody; MT6-MMP antibody; MT6MMP antibody; MTMMP6 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Synthetic peptide of Human MMP25
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：Antigen affinity purification
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產品提供形式：Liquid
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應用范圍：ELISA,IHC
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推薦稀釋比：
Application Recommended Dilution ELISA 1:2000-1:5000 IHC 1:50-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：May activate progelatinase A.
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基因功能參考文獻：
- In absolute mRNA levels, significant differences were found in expression of MMP2, MMP24, and MMP25 in gastric carcinoma compared with superficial gastritis. PMID: 24669030
- IL-2-upregulated MT6 cell-surface expression correlates with CD16 downmodulation. MT6, sequestered in intracellular compartments in unstimulated NK cells, translocates to the effector-target cell interface of CD16-mediated immunological synapses. PMID: 23851692
- MT6-MMP regulates neutrophil and monocyte chemotaxis and by generating "eat-me" signals upon vimentin cleavage potentially increases phagocytic removal of neutrophils to resolve inflammation. PMID: 22367194
- MT6-MMP is present in the membrane, granules and nuclear/endoplasmic reticulum/Golgi fractions of PMNs where it is displayed as a disulfide-linked homodimer of 120 kDa PMID: 20501611
- individuals with history of chronic airways inflammation (asthma and COPD) serum leukolysin may be a metabolic marker associated with chronic atopy-associated respiratory inflammation. PMID: 20337648
- Biochemical characterization of the cellular glycosylphosphatidylinositol-linked membrane type-6 matrix metalloproteinase. PMID: 20308072
- MMP25 is regulated by clusterin in vivo PMID: 12860995
- MT6-MMP may play a role in colon cancer and exhibit unique biochemical and structural properties that may regulate proteolytic function at the cell surface. PMID: 17513868
- the stem region of MT6-MMP is the dimerization interface, an event whose outcome imparts protease stability to the protein PMID: 18936094
- MMP-25 plays an important role in multiple sclerosis pathology PMID: 19726693
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亞細胞定位：Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side. Secreted, extracellular space, extracellular matrix.
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蛋白家族：Peptidase M10A family
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組織特異性：Expressed predominantly in leukocytes, lung and spleen. Expressed also in colon carcinoma, astrocytoma and glioblastomas.
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數據庫鏈接：
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