MLK4 Antibody
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中文名稱：MLK4兔多克隆抗體
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貨號(hào)：CSB-PA259340
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規(guī)格：￥2024
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圖片：
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Western blot analysis of extracts from HT-29 cells, using MAP3KL4 antibody.
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) MAP3K21 Polyclonal antibody
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Uniprot No.：
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基因名：MAP3K21
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Synthesized peptide derived from internal of Human MAP3KL4.
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免疫原種屬：Homo sapiens (Human)
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克隆類型：Polyclonal
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA,WB
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:3000 -
Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Negative regulator of TLR4 signaling. Does not activate JNK1/MAPK8 pathway, p38/MAPK14, nor ERK2/MAPK1 pathways.
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基因功能參考文獻(xiàn)：
- These results suggest that in the early response to stressful stimuli, MLK4beta-MLK3 binding is important for regulating MLK3 activity and MAPK signalling, and after prolonged periods of stress exposure, MLK4beta and MLK3 proteins decline via CHIP-dependent degradation. PMID: 28757353
- results uncover MLK4 as an upstream regulator of NF-kappaB signaling and a potential molecular target for the MES subtype of glioblastomas PMID: 26859459
- In establishing the role of MLK4 in intracellular signaling, we show it directly phosphorylates MEK1 (MAP2K1) and that MEK/ERK (MAPK1) signaling is impaired in MLK4 knockout cells PMID: 23319808
- MLK4 is a negative regulator of TLR4 signaling. PMID: 21602844
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蛋白家族：Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily
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數(shù)據(jù)庫(kù)鏈接：
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