MGAT4B Antibody

中文名稱：

MGAT4B兔多克隆抗體
貨號：

CSB-PA890781LA01HU
規格：

￥440
圖片：
Western Blot
Positive WB detected in: SH-SY5Y whole cell lysate, Jurkat whole cell lysate
All lanes: MGAT4B antibody at 3µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 64, 65 kDa
Observed band size: 64 kDa

IHC image of CSB-PA890781LA01HU diluted at 1:300 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) MGAT4B Polyclonal antibody
Uniprot No.：

Q9UQ53
基因名：

MGAT4B
別名：

3-D-mannoside beta-1 antibody; 3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B antibody; 4-N-acetylglucosaminyltransferase IVb antibody; Alpha 1 3 mannosyl glycoprotein beta 1 4 N acetylglucosaminyltransferase antibody; Alpha-1 antibody; Aminyltransferase antibody; GlcNAc T IVb antibody; GlcNAc-T IVb antibody; GNT IV antibody; GNT IVB antibody; GnT-IVb antibody; GNTIV antibody; GNTIVB antibody; Mannosyl (alpha 1 3) glycoprotein beta 1 4 N acetylglucosaminyltransferase isozyme B antibody; MGAT 4B antibody; mgat4b antibody; MGT4B_HUMAN antibody; N acetylglucosaminyltransferase IVb antibody; N glycosyl oligosaccharide glycoprotein antibody; N glycosyl oligosaccharide glycoprotein N acetylglucosaminyltransferase IVb antibody; N-acetylglucosaminyltransferase IVb antibody; N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVb antibody; UDP N acetylglucosamine alpha 1 3 D mannoside beta 1 4 N acetylglucosaminyltransferase IV antibody; UDP N acetylglucosamine alpha 1 3 D mannoside beta 1 4 N acetylglucosaminyltransferase IVb antibody; UDP-N-acetylglucosamine: alpha-1 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B protein (380-522AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，MGAT4B Antibody (CSB-PA890781LA01HU)，的標記方式是Non-conjugated。對于MGAT4B Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA890781LB01HU	MGAT4B Antibody, HRP conjugated	ELISA
FITC	CSB-PA890781LC01HU	MGAT4B Antibody, FITC conjugated
Biotin	CSB-PA890781LD01HU	MGAT4B Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, WB, IHC

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:5000
IHC	1:200-1:500

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N-linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains. Has lower affinities for donors or acceptors than MGAT4A, suggesting that, under physiological conditions, it is not the main contributor in N-glycan biosynthesis.
基因功能參考文獻：
1. UDP-galactose (SLC35A2) and UDP-N-acetylglucosamine (SLC35A3) Transporters Form Glycosylation-related Complexes with Mannoside Acetylglucosaminyltransferases (Mgats). PMID: 25944901
2. analysis of expression of N-acetylglucosaminyltransferase-IVa and IVb (GnT-IVa and b) in pancreatic cancer PMID: 16434023
3. GnT-IVa is more active than GnT-IVb under physiological conditions and it primarily contributes to the biosynthesis of N-glycans. PMID: 17006639
4. We investigated mRNA levels of glycosyltransferases, namely, N-acetylglucosaminyltransferase a (GnT)-IVb, and found that (GnT)-IVb expression was increased in HLE-cells Epirubicin resistant. PMID: 17488527
亞細胞定位：

Golgi apparatus membrane; Single-pass type II membrane protein.
蛋白家族：

Glycosyltransferase 54 family
組織特異性：

Widely expressed. Strongly overexpressed in pancreatic cancer.
數據庫鏈接：

HGNC: 7048

OMIM: 604561

KEGG: hsa:11282

STRING: 9606.ENSP00000338487

UniGene: Hs.567419

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