MFNG Antibody, FITC conjugated
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中文名稱：MFNG兔多克隆抗體, FITC偶聯(lián)
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貨號：CSB-PA013757LC01HU
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規(guī)格：￥880
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) MFNG Polyclonal antibody
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Uniprot No.：
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基因名：
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別名：MFNG; Beta-1,3-N-acetylglucosaminyltransferase manic fringe; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Recombinant Human Beta-1,3-N-acetylglucosaminyltransferase manic fringe protein (28-321AA)
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：FITC
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產(chǎn)品提供形式：Liquid
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Modulates NOTCH1 activity by modifying O-fucose residues at specific EGF-like domains resulting in inhibition of NOTCH1 activation by JAG1 and enhancement of NOTCH1 activation by DLL1 via an increase in its binding to DLL1.
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基因功能參考文獻(xiàn)：
- MFNG imposes a negative correlation between Jag1 and Notch, being high Jag1 in the absence of MFNG predictive of poor prognosis. PMID: 30065304
- Mfng is an oncogene acting through Notch-mediated induction of Pik3cg. PMID: 25808869
- down regulated in Papillomavirus-mediated cervical neoplasia. PMID: 15280477
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亞細(xì)胞定位：Golgi apparatus membrane; Single-pass type II membrane protein.
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蛋白家族：Glycosyltransferase 31 family
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數(shù)據(jù)庫鏈接：
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