MED21 Antibody

文獻引用 (1) 說明書

產品詳情

Uniprot No.：

Q13503
基因名：

MED21
別名：

MED21 antibody; SRB7 antibody; SURB7 antibody; Mediator of RNA polymerase II transcription subunit 21 antibody; Mediator complex subunit 21 antibody; RNA polymerase II holoenzyme component SRB7 antibody; RNAPII complex component SRB7 antibody; hSrb7 antibody
宿主：

Rabbit
反應種屬：

Human,Mouse
免疫原：

Synthesized peptide derived from the Internal region of Human Srb7.
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
產品提供形式：

Liquid
應用范圍：

IHC, ELISA

推薦稀釋比：

Application	Recommended Dilution
IHC	1:100-1:300
ELISA	1:20000

Protocols：

Immunohistochemistry (IHC) Protocol
ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
基因功能參考文獻：
1. Co-expressed yeast MED21 and MED7 in E. coli to determine structure. PMID: 15710619
2. Blocking MED1/MED21 expression caused hyperproliferation of keratinocytes PMID: 20520624
亞細胞定位：

Nucleus.
蛋白家族：

Mediator complex subunit 21 family
數據庫鏈接：

HGNC: 11473

OMIM: 603800

KEGG: hsa:9412

STRING: 9606.ENSP00000282892

UniGene: Hs.286145

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