MED14 Antibody
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中文名稱：MED14兔多克隆抗體
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貨號：CSB-PA070279
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規(guī)格：￥1090
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：MED14
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別名：Activator-recruited cofactor 150 kDa component antibody; ARC150 antibody; Cofactor required for Sp1 transcriptional activation subunit 2 antibody; CRSP complex subunit 2 antibody; DRIP150 antibody; EXLM1 antibody; hRGR1 antibody; MED14 antibody; MED14_HUMAN antibody; Mediator complex subunit 14 antibody; Mediator of RNA polymerase II transcription subunit 14 antibody; RGR1 antibody; RGR1 homolog antibody; Thyroid hormone receptor-associated protein complex 170 kDa component antibody; Transcriptional coactivator CRSP150 antibody; Trap170 antibody; Vitamin D3 receptor-interacting protein complex 150 kDa component antibody
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宿主：Rabbit
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反應(yīng)種屬：Human,Mouse
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免疫原：Synthesized peptide derived from the Internal region of Human CRSP150.
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：IHC, IF, ELISA
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推薦稀釋比：
Application Recommended Dilution IHC 1:100-1:300 IF 1:200-1:1000 ELISA 1:40000 -
Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
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基因功能參考文獻(xiàn)：
- Functional analysis implicates TNRC6A, NAT10, MED14, and WDR5 in RNA-mediated transcriptional activation. PMID: 28813667
- This results from a dramatically enhanced ability of MED14-containing complexes to associate with Pol II. PMID: 25383669
- VitD-mediated stimulation of GC anti-inflammatory affects human monocytes in a process involving GM-CSF and MED14 PMID: 23572530
- DRIP150 binds to ISGF3 and regulates transcription PMID: 12509459
- CRSP2 gene is expressed in the retina and its exact genomic location is on Xp11.4 between DXS1368 and DXS993 PMID: 12825353
- Coactivation of ERalpha by DRIP150 in ZR-75 cells is NR box-independent and requires a novel sequence with putative alpha-helical structure. PMID: 15625066
- MED14 and MED1 are used by glucocorticoid receptor in a gene-specific manner, providing a mechanism for promoter selectivity by glucocorticoid receptor PMID: 16239257
- Coactivator that enhances estrogen receptor alpha- and specificity protein (SP)-1-mediated transactivation in breast cancer cells. PMID: 17306756
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亞細(xì)胞定位：Nucleus.
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蛋白家族：Mediator complex subunit 14 family
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組織特異性：Ubiquitous.
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數(shù)據(jù)庫鏈接：
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