MCIDAS Antibody

中文名稱：

MCIDAS兔多克隆抗體
貨號：

CSB-PA518689LA01HU
規格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA518689LA01HU at dilution of 1:100
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) MCIDAS Polyclonal antibody
Uniprot No.：

D6RGH6
基因名：

MCIDAS
別名：

IDAS antibody; Mci antibody; MCI_HUMAN antibody; Multicilin antibody; Protein Idas antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Multicilin protein (3-110AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，MCIDAS Antibody (CSB-PA518689LA01HU)，的標記方式是Non-conjugated。對于MCIDAS Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA518689LB01HU	MCIDAS Antibody, HRP conjugated	ELISA
FITC	CSB-PA518689LC01HU	MCIDAS Antibody, FITC conjugated
Biotin	CSB-PA518689LD01HU	MCIDAS Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Transcription regulator specifically required for multiciliate cell differentiation. Acts in a multiprotein complex containing E2F4 and E2F5 that binds and activates genes required for centriole biogenesis. Required for the deuterosome-mediated acentriolar pathway. Plays a role in mitotic cell cycle progression by promoting cell cycle exit. Modulates GMNN activity by reducing its affinity for CDT1.
基因功能參考文獻：
1. MCIDAS mutations result in a mucociliary clearance disorder with reduced generation of multiple motile cilia.MCIDAS regulates CCNO and FOXJ1 expression. PMID: 25048963
2. The properties of the Idas-Geminin complex suggest it as the functional form of Idas and provide a possible mechanism to modulate Geminin activity PMID: 24064211
3. Idas as a novel Geminin binding partner, implicated in cell cycle progression, and a putative regulator of proliferation-differentiation decisions during development. PMID: 21543332
亞細胞定位：

Nucleus.
蛋白家族：

Geminin family
數據庫鏈接：

HGNC: 40050

OMIM: 614086

KEGG: hsa:345643

STRING: 9606.ENSP00000426359

UniGene: Hs.394578

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