MAPK8IP2 Antibody
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中文名稱：MAPK8IP2兔多克隆抗體
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貨號：CSB-PA008389
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規格：￥1090
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其他：
產品詳情
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Uniprot No.：
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基因名：
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別名：C jun amino terminal kinase interacting protein 2 antibody; C-jun-amino-terminal kinase-interacting protein 2 antibody; Homologous to mouse JIP 1 antibody; IB 2 antibody; IB-2 antibody; IB2 antibody; Islet brain 2 antibody; Islet-brain-2 antibody; JIP 2 antibody; JIP-2 antibody; JIP2 antibody; JIP2_HUMAN antibody; JNK interacting protein 2 antibody; JNK MAP kinase scaffold protein 2 antibody; JNK MAP kinase scaffold protein JIP2 antibody; JNK-interacting protein 2 antibody; MAPK8IP2 antibody; Mitogen activated protein kinase 8 interacting protein 2 antibody; Mitogen-activated protein kinase 8-interacting protein 2 antibody; PRKM8 interacting protein like antibody; PRKM8IPL antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Synthesized peptide derived from the C-terminal region of Human JIP-2.
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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產品提供形式：Liquid
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應用范圍：WB, IHC, IF, ELISA
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:2000 IHC 1:100-1:300 IF 1:200-1:1000 ELISA 1:20000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. JIP2 inhibits IL1 beta-induced apoptosis in insulin-secreting cells. May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins.
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基因功能參考文獻：
- Human IB2 mutation has a role as a contributing genetic factor in chromosome 22-associated cognitive disorders. PMID: 21048139
- there is a signaling module in which IB2 scaffolds a MLK3/MKK/p38delta kinase cascade. PMID: 12244047
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亞細胞定位：Cytoplasm.
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蛋白家族：JIP scaffold family
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組織特異性：Expressed mainly in the brain and pancreas, including insulin-secreting cells. In the nervous system, more abundantly expressed in the cerebellum, pituitary gland, occipital lobe and the amygdala. Also expressed in fetal brain. Very low levels found in ut
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數據庫鏈接：
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