MAP3K10 Antibody
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中文名稱：MAP3K10兔多克隆抗體
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貨號：CSB-PA131148
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規格：￥1100
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圖片：
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The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA131148(MAP3K10 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ×200)
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其他：
產品詳情
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Uniprot No.：
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基因名：MAP3K10
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別名：M3K10_HUMAN antibody; MAP3K 10 antibody; Map3k10 antibody; MEKK10 antibody; Mitogen activated protein kinase kinase kinase 10 antibody; Mitogen-activated protein kinase kinase kinase 10 antibody; Mixed lineage kinase 2 antibody; MKN28 derived nonreceptor type serine/threonine kinase antibody; MKN28 kinase antibody; MLK 2 antibody; MST antibody; Protein kinase MST antibody
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宿主：Rabbit
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反應種屬：Human,Mouse
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免疫原：Synthetic peptide of Human MAP3K10
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：Antigen affinity purification
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產品提供形式：Liquid
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應用范圍：ELISA,IHC
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推薦稀釋比：
Application Recommended Dilution ELISA 1:2000-1:5000 IHC 1:25-1:100 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Activates the JUN N-terminal pathway.
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基因功能參考文獻：
- MST interaction with MOB1 is not essential for development and tissue growth control. PMID: 28947795
- We identified a direct target of miR-155 as MAP3K10 in osteosarcoma PMID: 28214207
- A novel and important role for MAP3K10 in the proliferation and chemoresistance of pancreatic ductal adenocarcinoma. PMID: 23178452
- This study showed that show that RUNX3 is a principal and evolutionarily conserved component of the MST pathway. PMID: 21678419
- Mechanism of MAP kinase activation by TNF requires Src-dependent activation of Vav, activation of Rac/Cdc42, and the engagement of the Rac/Cdc42 interaction site on MLK3. PMID: 21979919
- Mechanism of MAP kinase activation by TNF requires Src-dependent activation of Vav, activation of Rac/Cdc42, and the engagement of the Rac/Cdc42 interaction site on MLK2 and 3. PMID: 21979919
- Data show that miR-181b contributed to proliferation of AML cells by targeting MLK2. PMID: 20596961
- MLK2 has a role in vesicle formation and endosome recycling by binding to clathrin PMID: 12105200
- demonstrate Alien-MLK2 interaction and also show that MLK2 is able to phosphorylate Alien; Alien, DAX-1 and thyroid hormone receptor mediated transcriptional silencing is strongly enhanced in the presence of active MLK2 PMID: 15062575
- MLK2 and -3 are required for activation of JNK and p38 by ectopically expressed GCK PMID: 17584736
- Hippocalcin and MLK2 were colocalized in the halo of Lewy bodies in Parkinson disease patients, and neither protein was detected in normal pigmented neurons. PMID: 19332348
- Mixed lineage kinase phosphorylates transcription factor E47 and inhibits TrkB expression to link neuronal death and survival pathways PMID: 19801649
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蛋白家族：Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily
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組織特異性：Expressed in brain and skeletal muscle.
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數據庫鏈接：
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