MAN2C1 Antibody, Biotin conjugated
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中文名稱：MAN2C1兔多克隆抗體, Biotin偶聯
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貨號：CSB-PA878885LD01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) MAN2C1 Polyclonal antibody
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Uniprot No.：
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基因名：MAN2C1
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別名：MAN2C1 antibody; MANA antibody; MANA1Alpha-mannosidase 2C1 antibody; EC 3.2.1.24 antibody; Alpha mannosidase 6A8B antibody; Alpha-D-mannoside mannohydrolase antibody; Mannosidase alpha class 2C member 1 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Alpha-mannosidase 2C1 protein (746-969AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Biotin
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Cleaves alpha 1,2-, alpha 1,3-, and alpha 1,6-linked mannose residues from glycoproteins. Involved in the degradation of free oligosaccharides in the cytoplasm.
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基因功能參考文獻：
- MAN2C1 may contribute to the verbal difficulties observed in microduplications and to the intellectual disability of microdeletion syndromes PMID: 27355585
- Man2C1 has dual functions: one in glycan catabolism and another in apoptotic signaling. PMID: 23486476
- MAN2C1 binds PTEN thereby inhibiting its phosphatidylinositol 3,4,5 triphosphate phosphatase activity PMID: 21556061
- MAN2C1 methylation levels modify cumulative traumatic burden on risk of post traumatic stress disorder PMID: 21508515
- regulation of Man2C1 expression is essential for maintaining efficient protein N-glycosylation PMID: 20978011
- Reduced antibody response to BSA was observed in transgenic mice, suggesting that specific antibody response to tumor antigens might be suppressed by hMan2c1 transgene. PMID: 19572206
- plays an important role in preventing oncosis-like death in BJAB cells PMID: 12643454
- Results suggest that inhibition of alpha-mannosidase Man2c1 gene expression enhances adhesion of Jurkat T cells. PMID: 16721356
- Inhibition of MAN2C1 gene expression suppresses growth of esophageal carcinoma cells through mitotic arrest and apoptosis. PMID: 19018777
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亞細胞定位：Cytoplasm.
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蛋白家族：Glycosyl hydrolase 38 family
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數據庫鏈接：
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