MAB21L1 Antibody, HRP conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) MAB21L1 Polyclonal antibody
Uniprot No.：

Q13394
基因名：

MAB21L1
別名：

MAB21L1 antibody; CAGR1 antibody; Nbla00126Putative nucleotidyltransferase MAB21L1 antibody; EC 2.7.7.- antibody; Protein mab-21-like 1 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Putative nucleotidyltransferase MAB21L1 protein (1-359AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

HRP
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Putative nucleotidyltransferase required for several aspects of embryonic development including normal development of the eye. It is unclear whether it displays nucleotidyltransferase activity in vivo. Binds single-stranded RNA (ssRNA).
基因功能參考文獻：
1. Mab21l1-/- osteoblasts also expressed higher levels of adipocyte genes and interferon-regulated genes at early stages of osteogenesis PMID: 29156428
2. offer a structure-based explanation for the effects of MAB21L2 mutations in patients with eye malformations PMID: 27271801
3. mab21 gene family members, mab21l1 and mab21l2, play important roles in regulating eye development. [review] PMID: 27558071
4. We hypothesize that MAB21L1 haploinsufficiency cause a previously undescribed syndrome with scrotal agenesis, ophthalmological anomalies, facial dysmorphism and gross psychomotor delay as remarkable hallmarks. PMID: 27103078
5. MEF is involved in PTH suppression of osteoblasts through activating the MKK4/JNK1 pathway and subsequently up-regulating Mab21l1 expression. PMID: 21465527
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亞細胞定位：

Nucleus.
蛋白家族：

Mab-21 family
組織特異性：

Expressed in brain, cerebellum and skeletal muscle.
數據庫鏈接：

HGNC: 6757

OMIM: 601280

KEGG: hsa:4081

STRING: 9606.ENSP00000369251

UniGene: Hs.584776

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