LTN1 Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) LTN1 Polyclonal antibody
Uniprot No.：

O94822
基因名：

LTN1
別名：

LTN1 antibody; C21orf10 antibody; C21orf98 antibody; KIAA0714 antibody; RNF160 antibody; ZNF294 antibody; HSPC087E3 ubiquitin-protein ligase listerin antibody; EC 2.3.2.27 antibody; RING finger protein 160 antibody; RING-type E3 ubiquitin transferase listerin antibody; Zinc finger protein 294 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human E3 ubiquitin-protein ligase listerin protein (462-591AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. Ubiquitination leads to VCP/p97 recruitment for extraction and degradation of the incomplete translation product.
基因功能參考文獻：
1. E3 ligase listerin accesses nascent polypeptides stalled at the Sec61 translocon via a gap in the ribosome-translocon junction near the Sec61 lateral gate. PMID: 25877867
2. Results show that Listerin specificity for nascent chain-60S complexes depends on nuclear export mediator factor. PMID: 25578875
亞細胞定位：

Cytoplasm, cytosol.
蛋白家族：

LTN1 family
數據庫鏈接：

HGNC: 13082

OMIM: 613083

KEGG: hsa:26046

STRING: 9606.ENSP00000373846

UniGene: Hs.288773

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