LSP1 Antibody
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中文名稱：LSP1兔多克隆抗體
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貨號：CSB-PA957371
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規格：￥2024
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圖片：
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Western blot analysis of extracts from HuvEc cells and K562 cells, using LSP1 antibody.
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) LSP1 Polyclonal antibody
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Uniprot No.：
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基因名：LSP1
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宿主：Rabbit
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反應種屬：Human
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免疫原：Synthesized peptide derived from internal of Human LSP1.
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免疫原種屬：Homo sapiens (Human)
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克隆類型：Polyclonal
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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產品提供形式：Liquid
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應用范圍：ELISA,WB
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:3000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
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靶點詳情
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功能：May play a role in mediating neutrophil activation and chemotaxis.
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基因功能參考文獻：
- LSP1 rs3817198 T > C polymorphism is associated with increased risk of breast cancer, especially in Caucasian and Asian populations [meta-analysis] PMID: 27590509
- These results show that LSP1 is critical regulator of actomyosin contractility in primary macrophages. PMID: 29410425
- Underexpression of LSP1 is associated with Breast Cancer Recurrence. PMID: 27165221
- LSP1 rs569550 and rs592373 polymorphisms are both risk factors for breast cancer. PMID: 26191300
- the importance of LSP1 Copy number variations and LSP1 insufficiency in the pathogenesis of rheumatoid arthritis, is reported. PMID: 26554018
- The breast cancer SNP LSP1 rs3817198 was associated with an increased risk of lung cancer (odds ratio: 1.10) This association was strongest for women with adenocarcinoma (P = 1.2x10(-4)). PMID: 24681604
- Data indicate that slit2N alters the localization and binding of Robo1 to WASp and LSP1 in HIV-1-gp120-treated immature dendritic cells (iDCs). PMID: 23119100
- Single nucleotide polymorphism in LSP1 is associated with breast cancer. PMID: 22454379
- The LSP1 rs3817198T>C polymorphism is a low-penetrant risk factor for developing breast cancer but may not be in Africans. PMID: 21127985
- Low-risk variants of LSP1 is associated with familial breast cancer. PMID: 19856316
- The LSP1 and 2q35 SNPs appear to interact multiplicatively on breast cancer risk for BRCA2 mutation carriers. PMID: 19656774
- LSP1 interacts with F-actin and the cytoskeleton through residues downstream of amino acid residue 230. The cytoskeleton binding site of mouse LSP1 maps to the 300-330 interval. PMID: 12972289
- Leukocyte-specific protein 1 is a cytoskeletal targeting protein for the ERK/MAP kinase pathway PMID: 15090600
- LSP1 protein facilitates virus transport into the proteasome after its interaction with DC-SIGN through its interaction with cytoskeletal proteins. PMID: 17296787
- MK2-regulated LSP1 phosphorylation is involved in stabilization of F-actin polarization during neutrophil chemotaxis. PMID: 17481585
- DC-SIGN was constitutively associated with a signalosome complex consisting of the scaffold proteins LSP1, KSR1 and CNK and the kinase Raf-1 PMID: 19718030
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亞細胞定位：Cell membrane; Peripheral membrane protein; Cytoplasmic side.
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組織特異性：Activated T-lymphocytes.
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數據庫鏈接：
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