LSM14A Antibody
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中文名稱：LSM14A兔多克隆抗體
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貨號：CSB-PA013203GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：LSM14A
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別名：AlphaSNBP antibody; C19orf13 antibody; Chromosome 19 open reading frame 13 antibody; DKFZp434D1335 antibody; FAM61A antibody; Family with sequence similarity 61 member A antibody; hRAP55 antibody; hRAP55A antibody; LS14A_HUMAN antibody; LSM14 homolog A (SCD6 S cerevisiae) antibody; LSM14 homolog A antibody; LSM14A antibody; Protein FAM61A antibody; Protein LSM14 homolog A antibody; Protein SCD6 homolog antibody; Putative alpha synuclein binding protein antibody; Putative alpha-synuclein-binding protein antibody; RAP55 antibody; RNA associated protein 55 antibody; RNA-associated protein 55A antibody; SCD6 homolog A (S cerevisiae) antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human LSM14A
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB,IHC
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Essential for formation of P-bodies, cytoplasmic structures that provide storage sites for translationally inactive mRNAs and protect them from degradation. Acts as a repressor of mRNA translation. May play a role in mitotic spindle assembly.
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基因功能參考文獻：
- alpha-synuclein p.A53V homozygous mutation leads to a distinct phenotype of progressive parkinsonism and cognitive decline, commonly observed in patients with SNCA missense mutation or multiplications PMID: 28666710
- Excessive iron and alpha-synuclein oligomer in brain commonly contributed to pure apathy of PD through potential mechanism of oxidative stress. PMID: 26940028
- RAP55/LSM14 binds directly the tubulin and that is implicated in the process of the mitotic spindle stabilization PMID: 26339800
- RAP55 is important for the assembly of cytoplasmic mRNP granules and that PRMT1 is required for RAP55A to localize to P-bodies. PMID: 22614839
- The NS1 protein of influenza A virus interacts with cellular processing bodies and stress granules through RNA-associated protein 55 (RAP55) during virus infection. PMID: 22973032
- LSm14A is a processing body-associated sensor of viral nucleic acids that initiates cellular antiviral response in the early phase of viral infection. PMID: 22745163
- this protein family has evolved a common and fundamental role in the control of mRNA translation. Human RAP55A is an autoantigen detected in the serum of patients with primary biliary cirrhosis (PBC). PMID: 18723115
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亞細胞定位：Cytoplasm, P-body. Cytoplasm, cytoskeleton, spindle. Cytoplasm, Stress granule.
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蛋白家族：LSM14 family
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數據庫鏈接：
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