LMOD1 Antibody

說明書

中文名稱：

LMOD1兔多克隆抗體
貨號：

CSB-PA013013ESR1HU
規格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA013013ESR1HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human glioma using CSB-PA013013ESR1HU at dilution of 1:100
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) LMOD1 Polyclonal antibody
Uniprot No.：

P29536
基因名：

LMOD1
別名：

1D antibody; 64 kDa autoantigen 1D antibody; 64 kDa autoantigen 1D3 antibody; 64 kDa autoantigen D1 antibody; 9530015K06Rik antibody; D1 antibody; Leiomodin antibody; Leiomodin-1 antibody; Lmod1 antibody; LMOD1_HUMAN antibody; muscle form antibody; SM LMOD antibody; SM-Lmod antibody; SMLMOD antibody; Smooth muscle leiomodin antibody; Thyroid associated ophthalmopathy autoantigen antibody; Thyroid-associated ophthalmopathy autoantigen antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Leiomodin-1 protein (29-187AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
產品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Mediates nucleation of actin filaments.
基因功能參考文獻：
1. Loss of LMOD1 results in a reduction of filamentous actin, elongated cytoskeletal dense bodies, and impaired intestinal smooth muscle contractility. PMID: 28292896
2. Key role for miR-214 in modulation of MEF2C-MYOCD-LMOD1 signaling. PMID: 27144530
3. Lmod1 is a new SMC-restricted SRF/MYOCD target gene. PMID: 22157009
4. Lmod1 is a component of the smooth muscle contractile apparatus extractable by high salt, not a transmembrane protein as previously predicted. PMID: 11350761
5. Lmod1, formerly the 64kD human autoantigen D1, is expressed in smooth muscle and striated extraocular slow muscle fibers, colocalized with myosin in the contractile apparatus. Protein levels are unaltered by hyperthyroidism. PMID: 10520227
6. Lmod1 is a member of the Tropomodulin family of actin binding proteins, and is most highly expressed in smooth muscle. PMID: 11318603
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亞細胞定位：

Cytoplasm, myofibril, sarcomere. Cytoplasm, cytoskeleton.
蛋白家族：

Tropomodulin family
組織特異性：

Detected in lung vascular smooth muscle (at protein level). Detected in thyroid and extraocular smooth muscle, but not skeletal muscle. Detected in heart, aorta, skeletal muscle, colon, urinary bladder, uterus, stomach, and small intestine.
數據庫鏈接：

HGNC: 6647

OMIM: 602715

KEGG: hsa:25802

STRING: 9606.ENSP00000356257

UniGene: Hs.519075

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