LHX2 Antibody

中文名稱：

LHX2兔多克隆抗體
貨號：

CSB-PA012920LA01HU
規格：

￥440
圖片：
Western Blot
Positive WB detected in: Rat kidney tissue
All lanes: LHX2 antibody at 5.43μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 45 kDa
Observed band size: 45 kDa

Immunofluorescence staining of Hela cells with CSB-PA012920LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
其他：

產品詳情
產品評價
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靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) LHX2 Polyclonal antibody
Uniprot No.：

P50458
基因名：

LHX2
別名：

hLhx2 antibody; Homeobox protein LH-2 antibody; Homeobox protein LH2 antibody; LH2 antibody; LHX2 antibody; LHX2_HUMAN antibody; LIM homeobox 2 antibody; LIM homeobox protein 2 antibody; LIM HOX gene 2 antibody; LIM/homeobox protein Lhx2 antibody
宿主：

Rabbit
反應種屬：

Human, Rat
免疫原：

Recombinant Human LIM/homeobox protein Lhx2 protein (197-377AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，LHX2 Antibody (CSB-PA012920LA01HU)，的標記方式是Non-conjugated。對于LHX2 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA012920LB01HU	LHX2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA012920LC01HU	LHX2 Antibody, FITC conjugated
Biotin	CSB-PA012920LD01HU	LHX2 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, WB, IF

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:5000
IF	1:50-1:200

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Acts as a transcriptional activator. Stimulates the promoter of the alpha-glycoprotein gene. Transcriptional regulatory protein involved in the control of cell differentiation in developing lymphoid and neural cell types.
基因功能參考文獻：
1. These data indicate that Lhx2 is capable of blocking proliferation of T-ALL-derived cells by both LMO2-dependent and -independent means. We propose Lhx2 as a new molecular tool for anti-T-ALL drug development. PMID: 29278703
2. Findings demonstrate that miR-1238 inhibit the proliferation of NSCLC cells at least partly via repression of LHX2, shedding light on the mechanistic interaction of miR-1238 and LHX2 in NSCLC carcinogenesis. PMID: 26189214
3. Results show that LHX2 is overexpressed in pancreatic ductal adenocarcinoma cells and is involved in promoting cancer cell proliferation and enhanced tumor development. PMID: 25324171
4. Lhx2 directly regulates tanycyte specification and differentiation in the hypothalamus. PMID: 25505333
5. This study demonistrated that LHx2 regulates the development of the forebrain hem system. PMID: 23307637
6. The data indicate a dual role of Lhx2 during EMT and tumor progression: by inducing the expression of PDGF-B, Lhx2 provokes an autocrine PDGF-B/PDGFRbeta loop required for cell migration, invasion and metastatic dissemination PMID: 24423492
7. The findings indicate that LHX2 regulates the transcription of downstream intrinsic and extrinsic molecules that are essential for early neural differentiation. PMID: 23804753
8. These results suggest that if LHX2 is involved in pituitary hormone deficiency associated with posterior pituitary and ocular defects, it would be a rare cause of this disease condition. PMID: 22535646
9. Mutations in LHX2 do not represent a frequent cause of micro/anophthalmia. PMID: 21203406
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亞細胞定位：

Nucleus.
數據庫鏈接：

HGNC: 6594

OMIM: 603759

KEGG: hsa:9355

STRING: 9606.ENSP00000362717

UniGene: Hs.696425

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