LBH Antibody, Biotin conjugated
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中文名稱：LBH兔多克隆抗體, Biotin偶聯
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貨號：CSB-PA700659LD01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) LBH Polyclonal antibody
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Uniprot No.：
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基因名：LBH
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別名：hLBH antibody; lbh antibody; LBH_HUMAN antibody; Limb bud and heart development antibody; Limb bud and heart development homolog (mouse) antibody; Protein LBH antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Protein LBH protein (1-105AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Biotin
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Transcriptional activator which may act in mitogen-activated protein kinase signaling pathway.
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基因功能參考文獻：
- LBH was significantly down-regulated in lung cancer tissue samples and was correlated with the prognosis and clinical characteristics of lung cancer patients. Survival analysis revealed that LBH-negative expression was associated with poor overall survival of LUAD patients (P = 0.021). PMID: 29788015
- Low LBH level, caused by a rheumatoid arthritis risk allele, is a risk factor for aggressive fibroblast-like synoviocyte behavior. PMID: 27159840
- The expression levels of LBH mRNA in patients with SLE were significantly decreased compared with those in normal controls (P < 0.001). No significant differences were found between LBH mRNA expression levels and SLE disease activity scores, SNP rs7579944 and rs906868. PMID: 26134586
- LBH normally induces NPC cell cycle arrest at the G1/S transition, and LBH can suppress the growth of transplanted NPC tumors in vivo by downregulating LMP1-mediated NF-kappaB transcriptional activity. PMID: 25557837
- LBH is a candidate gene for synovial pathology in rheumatoid arthritis. It is regulated by growth factors and modulates cell growth in primary fibroblast-like synoviocytes. PMID: 25707478
- results showed that the interaction of LBH and alphaB-crystallin may inhibit synergistically the transcriptional regulation of p53 and p21 PMID: 20587334
- LBH is aberrantly overexpressed in mammary tumors of mouse mammary tumor virus (MMTV)-Wnt1-transgenic mice and in aggressive basal subtype human breast cancers that display Wnt/beta-catenin hyperactivation. PMID: 20606007
- LBH is implicated as a candidate gene for congenital heart disease associated with partial trisomy 2p syndrome PMID: 15958514
- These results suggest that hLBH proteins may act as a transcriptional activator in mitogen-activated protein kinase signaling pathway to mediate cellular functions. PMID: 17390236
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亞細胞定位：Nucleus. Cytoplasm.
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蛋白家族：LBH family
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組織特異性：Highly expressed in heart, and expressed at low levels in placenta, lung, skeletal muscle, kidney and liver.
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數據庫鏈接：
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