LAMB Antibody

^{Rare Species}

說明書

中文名稱：

LAMB兔多克隆抗體
貨號：

CSB-PA365810XA01ENV
規(guī)格：

￥440
圖片：
Western Blot
Positive WB detected in Recombinant protein
All lanes: LAMB antibody at 1:2000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 29.8 kDa
Observed band size: 31 kDa
其他：

產(chǎn)品詳情
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情

產(chǎn)品詳情

Uniprot No.：

P02943
基因名：

LAMB
別名：

Maltoporin (Lambda receptor protein) (Maltose-inducible porin) lamB malB b4036 JW3996
反應(yīng)種屬：

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
免疫原：

Recombinant Escherichia coli (strain K12) LAMB protein
免疫原種屬：

Escherichia coli (strain K12)
標(biāo)記方式：

Non-conjugated
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Protein G
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA, WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

功能：

Involved in the transport of maltose and maltodextrins. Indispensable for translocation of maltodextrins (alpha 1-4 linked polyglucosyls) containing more than three glucosyl moieties. A hydrophobic path ('greasy slide') of aromatic residues serves to guide and select the sugars for transport through the channel. Also acts as a receptor for several bacteriophages including lambda. Binds maltosaccharides; when LamB binds starch in soft agar, it inhibits motility.
基因功能參考文獻(xiàn)：
1. Our data indicate that the negative regulation by LamB is widely detected in antibiotic-resistant E. coli. LamB serves as a porin to influx an antibiotic and is interacted with Odp1. PMID: 24412198
2. Results report the crystallization of E. coli maltoporin in a new crystal form; the crystals belonged to the trigonal R3 space group and diffracted to 1.9 A resolution. PMID: 21206039
3. downregulation of LamB expression in the CTC-resistant E. coli strain and the increased antibiotic resistance in its gene-deleted strain suggested a negative regulation mechanism in E. coli in response to CTC PMID: 20718490
4. demonstrated that LamB moves along the bacterial surface and that these movements are restricted by an underlying dynamic spiral pattern PMID: 15341654
5. all aromatic residues provide some steric hindrance for ion transport through LamB PMID: 16095613
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亞細(xì)胞定位：

Cell outer membrane; Multi-pass membrane protein.
蛋白家族：

Porin LamB (TC 1.B.3) family
數(shù)據(jù)庫鏈接：

KEGG: ecj:JW3996

STRING: 316385.ECDH10B_4225

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