Kng1 Antibody

Name: Kng1 Antibody
Brand: CUSABIO
SKU: CSB-PA012479LA01RA

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說明書

產品詳情

產品名稱：

Rabbit anti-Rattus norvegicus (Rat) Kng1 Polyclonal antibody
Uniprot No.：

P08934
基因名：

Kng1
別名：

Kng1 antibody; Kng antibody; Kininogen-1 [Cleaved into: Kininogen-1 heavy chain; Bradykinin; Kininogen-1 light chain] antibody
宿主：

Rabbit
反應種屬：

Rat
免疫原：

Recombinant Rat Kininogen-1 protein (2-110AA)
免疫原種屬：

Rattus norvegicus (Rat)

標記方式：

Non-conjugated

本頁面中的產品，Kng1 Antibody (CSB-PA012479LA01RA)，的標記方式是Non-conjugated。對于Kng1 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA012479LB01RA	Kng1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA012479LC01RA	Kng1 Antibody, FITC conjugated
Biotin	CSB-PA012479LD01RA	Kng1 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

(1) Kininogens are inhibitors of thiol proteases; (2) HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII; (3) HMW-kininogen inhibits the thrombin- and plasmin-induced aggregation of thrombocytes; (4) the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects: (4A) influence in smooth muscle contraction, (4B) induction of hypotension, (4C) natriuresis and diuresis, (4D) decrease in blood glucose level, (4E) it is a mediator of inflammation and causes (4E1) increase in vascular permeability, (4E2) stimulation of nociceptors (4E3) release of other mediators of inflammation (e.g. prostaglandins), (4F) it has a cardioprotective effect (directly via bradykinin action, indirectly via endothelium-derived relaxing factor action); (5) LMW-kininogen inhibits the aggregation of thrombocytes; (6) LMW-kininogen is in contrast to HMW-kininogen not involved in blood clotting.
基因功能參考文獻：
1. High-molecular-weight kininogen and its peptide fragments modulate arterial thrombosis after arterial injury. PMID: 17293494
亞細胞定位：

Secreted, extracellular space.
組織特異性：

Plasma.
數據庫鏈接：

KEGG: rno:25087

STRING: 10116.ENSRNOP00000065146

UniGene: Rn.128333

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