KLF7 Antibody
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中文名稱：KLF7兔多克隆抗體
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貨號：CSB-PA959499
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規格：￥1100
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圖片：
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The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA959499(KLF7 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200) -
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA959499(KLF7 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
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其他：
產品詳情
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Uniprot No.：
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基因名：KLF7
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別名：KLF7 antibody; KLF7_HUMAN antibody; Krueppel like factor 7 antibody; Krueppel-like factor 7 antibody; Kruppel like factor 7 antibody; Ubiquitous krueppel like factor antibody; Ubiquitous krueppel-like factor antibody; UKLF antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Fusion protein of Human KLF7
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：Antigen affinity purification
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產品提供形式：Liquid
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應用范圍：ELISA,IHC
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推薦稀釋比：
Application Recommended Dilution ELISA 1:1000-1:5000 IHC 1:50-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Transcriptional factor. Plays a critical role in neuronal morphogenesis and survival of sensory neurons. Represses the corneal epithelium differentiation. Acts also as a metabolic regulator, by modulating insulin sensitivity in pancreatic beta cells and skeletal muscle cells. Inhibits transcriptional inducers of adipogenesis and has a repressive role in the expression of several adipokines, including leptin.
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基因功能參考文獻：
- Kruppel family member KLF7 promotes the corneal progenitor cell state; on many genes, KLF7 antagonized the corneal differentiation-promoting KLF4. PMID: 28916725
- KLF7 has an important role in gastric cancer (GC) progression, as it inhibits GC cell migration and may serve as a prognostic marker PMID: 28977783
- Higher expression of TLR4 and KLF7 may play a vital role in the process of inflammation induced by obesity in visceral adipose tissue PMID: 27714571
- a dominant mutation in FBXO38 causes adult-onset, progressive spinal muscular atrophy with calf predominance PMID: 24207122
- KLF7 was upregulated by morphine at both the transcriptional and the translational levels, promoting cell growth up to day 4 PMID: 14644156
- The gene encoding KLF7 is a novel candidate for conferring genetic susceptibility to type 2 diabetes. PMID: 15937668
- KLF7 may contribute to the pathogenesis of type 2 diabetes through an impairment of insulin biosynthesis and secretion in pancreatic beta-cells and a reduction of insulin sensitivity in peripheral tissues. PMID: 16339272
- We identified a novel association between the minor A-allele of KLF7 and protection against obesity in the Danish population PMID: 19147600
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亞細胞定位：Nucleus.
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蛋白家族：Krueppel C2H2-type zinc-finger protein family
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組織特異性：Widely expressed.
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數據庫鏈接：
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