KCNN1 Antibody
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中文名稱：KCNN1兔多克隆抗體
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貨號：CSB-PA012083GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：KCNN1
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別名：KCNN1; SK; Small conductance calcium-activated potassium channel protein 1; SK1; SKCa 1; SKCa1; KCa2.1
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human KCNN1
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization.
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基因功能參考文獻：
- SK current is increased via the enhanced activation of CaMKII in patients with atrial fibrillation. PMID: 29737974
- Differentiated dopaminergic neurons expressed low levels of SK2 channels and high levels of SK1 and SK3 channels. PMID: 24434522
- Decreased expression of small-conductance Ca2+-activated K+ channels SK1 and SK2 in human chronic atrial fibrillation. PMID: 22154908
- IK1-like immunoreactivity is observed in enteric neurons of human colon, with a significant decrease of IK1-positive cells in inflamed colon from patients with Crohn's disease and ulcerative colitis. PMID: 12598727
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亞細胞定位：Membrane; Multi-pass membrane protein.
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蛋白家族：Potassium channel KCNN family, KCa2.1/KCNN1 subfamily
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數據庫鏈接：
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