KCNK10 Antibody
-
中文名稱：KCNK10兔多克隆抗體
-
貨號：CSB-PA345388
-
規(guī)格：￥1090
-
圖片：
-
Western blot analysis of 1) Mouse BrainTissue, 2)Rat Brain Tissue, 3) Jurkat with KCNK10(TREK-2) Rabbit pAb diluted at 1:2,000. -
Immunohistochemical analysis of paraffin-embedded Rat BrainTissue using KCNK10 (TREK-2) Rabbit pAb diluted at 1:200.
-
-
其他：
產(chǎn)品詳情
-
Uniprot No.：
-
基因名：KCNK10
-
別名：KCNK10; TREK2; Potassium channel subfamily K member 10; Outward rectifying potassium channel protein TREK-2; TREK-2 K(+ channel subunit
-
宿主：Rabbit
-
反應(yīng)種屬：Human,Mouse,Rat
-
免疫原：Synthetic Peptide
-
免疫原種屬：Homo sapiens (Human)
-
標(biāo)記方式：Non-conjugated
-
純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen.
-
濃度：It differs from different batches. Please contact us to confirm it.
-
保存緩沖液：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
-
產(chǎn)品提供形式：Liquid
-
應(yīng)用范圍：WB, IHC, ELISA
-
推薦稀釋比：
Application Recommended Dilution WB 1:1000-2000 IHC 1:100-200 -
Protocols：
-
儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
-
用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情
-
功能：Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents. Activated by arachidonic acid and other naturally occurring unsaturated free fatty acids.
-
基因功能參考文獻(xiàn)：
- The M2-glycine hinge controls the macroscopic currents of TREK1 channels. PMID: 28676394
- This study showed that KCNK10 gene involved in neuronal growth and cerebellum development and associated with neurological and psychological disorders. PMID: 26381449
- The selectivity filter conformations of alternative translation initiation isoforms and wild type human TREK-2 are similar in the S4 site and pHo position. PMID: 26271386
- Results suggest that the cytosolic C-terminal domain and the bottom of transmembrane segment M2 are required for the 2-aminoethoxydiphenyl borate activation on TREK-2 channels PMID: 25982558
- How ion channels sense mechanical force: insights from mechanosensitive K2P channels TRAAK, TREK1, and TREK2. PMID: 26332952
- Modulation of K2P 2.1 and K2P 10.1 K(+) channel sensitivity to carvedilol by alternative mRNA translation initiation PMID: 25168769
- PLD2, but not PLD1, directly binds to the C terminus of TREK1 and TREK2. PMID: 25197053
- crystal structures of TREK-2 channel in 2 conformations and in complex with norfluoxetine, a state-dependent blocker of TREK channels; results provide an explanation for TREK channel mechanosensitivity, regulation by diverse stimuli and possible off-target effects of Prozac PMID: 25766236
- High TREK-2 expression is associated with epithelial ovarian cancer. PMID: 23479219
- Tissue-specific mRNA splicing regulates alternative translation initiation (ATI) of human K(2P)10.1 K+ background channels via recombination of 5 nucleotide motifs. PMID: 21669980
- Expression pattern and functional characteristics of two novel splice variants of the two-pore-domain potassium channel TREK-2. PMID: 11897838
- Predicts the role of TREK-2 in brain ischemia, memory and other tissues.[REVIEW] PMID: 17689202
顯示更多
收起更多
-
亞細(xì)胞定位：Membrane; Multi-pass membrane protein.
-
蛋白家族：Two pore domain potassium channel (TC 1.A.1.8) family
-
組織特異性：Abundantly expressed in pancreas and kidney and to a lower level in brain, testis, colon, and small intestine. Isoform b is strongly expressed in kidney (primarily in the proximal tubule) and pancreas, whereas isoform c is abundantly expressed in brain.
-
數(shù)據(jù)庫鏈接：
Most popular with customers
-
-
YWHAB Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC, IF, FC
Species Reactivity: Human, Mouse, Rat
-
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC
Species Reactivity: Human
-
-
-
-
-
