JMJD1C Antibody

中文名稱：

JMJD1C兔多克隆抗體
貨號：

CSB-PA624030HA01HU
規格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA624030HA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human melanoma using CSB-PA624030HA01HU at dilution of 1:100
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) JMJD1C Polyclonal antibody
Uniprot No.：

Q15652
基因名：

JMJD1C
別名：

JHD2C_HUMAN antibody; Jmjd1c antibody; Jumonji domain containing 1C antibody; Jumonji domain-containing protein 1C antibody; Probable JmjC domain-containing histone demethylation protein 2C antibody; Thryoid receptor interacting protein antibody; Thyroid receptor-interacting protein 8 antibody; TR-interacting protein 8 antibody; TRIP-8 antibody; TRIP8 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Probable JmjC domain-containing histone demethylation protein 2C protein (539-648AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，JMJD1C Antibody (CSB-PA624030HA01HU)，的標記方式是Non-conjugated。對于JMJD1C Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA624030HB01HU	JMJD1C Antibody, HRP conjugated	ELISA
FITC	CSB-PA624030HC01HU	JMJD1C Antibody, FITC conjugated
Biotin	CSB-PA624030HD01HU	JMJD1C Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Probable histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May be involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes.
基因功能參考文獻：
1. Study provides evidence that SNPs of JMJD1C and KCNQ1 are prospectively associated with the risk of type 2 diabetes (T2D) in Korean population. Additionally, CDKAL1 may not be associated with T2D onset over the age of 40. PMID: 28406950
2. JMJD1C is one of the target genes of hsa-miR-590- 3p. PMID: 27064872
3. Our findings indicate that mutations in JMJD1C contribute to the development of Rett syndrome and intellectual disability. PMID: 26181491
4. genetic variants in the androgen-related genes CYP17A1 and JMJD1C might be associated with risk of Barrett's esophagus (BE) and esophageal adenocarcinoma (EAC). PMID: 26414697
5. Histone modifier genes (JMJD1C, RREB1, MINA, KDM7A) alter conotruncal heart phenotypes in 22q11.2 deletion syndrome. PMID: 26608785
6. JMJD1C is directly recruited by RUNX1-RUNX1T1 to its target genes and regulates their expression by maintaining low H3K9 dimethyl (H3K9me2) levels PMID: 26494788
7. Depletion of JMJD1C impairs expansion and colony formation of leukemic cell lines, with the strongest effect observed in the MLL-rearranged ALL cell line SEM. PMID: 24501218
8. JMJD1C represses neural differentiation of hESCs at least partially by epigenetically sustaining miR-302 expression PMID: 24318875
9. JMJD1C regulates the RAP80-BRCA1 branch of this DNA-damage response (DDR) pathway. PMID: 24240613
10. No evidence for JMJD1C histone demethylase activity towards H3K9. PMID: 23593242
11. Observational study of gene-disease association. (HuGE Navigator) PMID: 20648472
12. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
13. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) PMID: 20526338
14. TRIP8 gene codes for a protein predicted to be a transcriptional regulator associated with nuclear thyroid hormone receptors. Positional candidate gene for autism. PMID: 17290275
15. the discovery of a new Receptors, Androgen coactivator which belongs to the JmjC containing enzyme family as a novel variant of JMJD1C PMID: 17353003
16. Human JMJD1C variant 2 with TRI8H1, TRI8H2, and JmjC domains showed 85.7% total-amino-acid identity with mouse Jmjd1c. PMID: 17549425
17. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) PMID: 19936222
18. Observational study of gene-disease association. (HuGE Navigator) PMID: 16385451
19. Observational study, meta-analysis, and genome-wide association study of gene-disease association. (HuGE Navigator) PMID: 18940312
顯示更多

收起更多
亞細胞定位：

Nucleus.
蛋白家族：

JHDM2 histone demethylase family
數據庫鏈接：

HGNC: 12313

OMIM: 604503

KEGG: hsa:221037

STRING: 9606.ENSP00000382204

UniGene: Hs.413416

Most popular with customers

YWHAB Recombinant Monoclonal Antibody

Applications: ELISA, WB, IHC, IF, FC

Species Reactivity: Human, Mouse, Rat
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody

Applications: ELISA, WB, IHC

Species Reactivity: Human
XRCC5 Recombinant Monoclonal Antibody

Applications: ELISA, WB, IHC, IF

Species Reactivity: Human
XPNPEP1 Recombinant Monoclonal Antibody

Applications: ELISA, IHC, FC

Species Reactivity: Human
XDH Recombinant Monoclonal Antibody

Applications: ELISA, WB, IHC

Species Reactivity: Human
WT1 Recombinant Monoclonal Antibody

Applications: ELISA, WB, IHC

Species Reactivity: Human
WDR5 Recombinant Monoclonal Antibody

Applications: ELISA, IHC, FC

Species Reactivity: Human
VIM Recombinant Monoclonal Antibody

Applications: ELISA, IHC, IF

Species Reactivity: Human