ISX Antibody

中文名稱：

ISX兔多克隆抗體
貨號：

CSB-PA011854LA01HU
規格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human endometrial cancer using CSB-PA011854LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human glioma using CSB-PA011854LA01HU at dilution of 1:100
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) ISX Polyclonal antibody
Uniprot No.：

Q2M1V0
基因名：

ISX
別名：

DKFZp781N2395 antibody; Intestine-specific homeobox antibody; Isx antibody; ISX_HUMAN antibody; MGC138417 antibody; OTTHUMP00000028558 antibody; Pancreas intestine homeodomain transcription factor antibody; Pix 1 antibody; RAX like homeobox antibody; RAX-like homeobox antibody; RAXLX antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Intestine-specific homeobox protein (1-245AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，ISX Antibody (CSB-PA011854LA01HU)，的標記方式是Non-conjugated。對于ISX Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA011854LB01HU	ISX Antibody, HRP conjugated	ELISA
FITC	CSB-PA011854LC01HU	ISX Antibody, FITC conjugated
Biotin	CSB-PA011854LD01HU	ISX Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Transcription factor that regulates gene expression in intestine. May participate in vitamin A metabolism most likely by regulating BCO1 expression in the intestine.
基因功能參考文獻：
1. our results indicate that E2F1 is an important downstream gene of ISX in hepatoma progression. PMID: 27175585
2. Results show that ISX expression mediated AHR-induced tumorigenesis in hepatocellular carcinoma. PMID: 28398627
3. Overall, our results identified a feed-forward mechanism of immune suppression in hepatocellular carcinoma organized by ISX, which involves kynurenine-AHR signaling and PD-L1, offering insights into immune escape by hepatocellular carcinoma PMID: 28625979
4. ISX expression induced by H. pylori infection may lead to intestinal metaplasia and hyperproliferation of gastric mucosa through CDX1/2 and cyclinD1 expression, contributing to gastric carcinogenesis. PMID: 26872890
5. Genetics and diet regulate vitamin A production via the homeobox transcription factor ISX PMID: 23393141
6. our results highlight ISX as an important regulator in hepatoma progression with significant potential as a prognostic and therapeutic target in HCCs. PMID: 23221382
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亞細胞定位：

Nucleus.
數據庫鏈接：

HGNC: 28084

OMIM: 612019

KEGG: hsa:91464

STRING: 9606.ENSP00000311492

UniGene: Hs.567637

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