BBS19 antibody; Ift27 antibody; IFT27_HUMAN antibody; Intraflagellar transport 27 antibody; Intraflagellar transport protein 27 homolog antibody; Putative GTP binding protein RAY like antibody; Putative GTP-binding protein RAY-like antibody; Rab like protein 4 antibody; RAB member of RAS oncogene family like 4 antibody; Rab-like protein 4 antibody; RAYL antibody
宿主:
Rabbit
反應(yīng)種屬:
Human
免疫原:
Recombinant Human Intraflagellar transport protein 27 homolog protein (1-186AA)
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期:
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Small GTPase-like component of the intraflagellar transport (IFT) complex B that promotes the exit of the BBSome complex from cilia via its interaction with ARL6. Not involved in entry of the BBSome complex into cilium. Prevents aggregation of GTP-free ARL6. Required for hedgehog signaling. Forms a subcomplex within the IFT complex B with IFT25. Its role in intraflagellar transport is mainly seen in tissues rich in ciliated cells such as kidney and testis. Essential for male fertility, spermiogenesis and sperm flagella formation. Plays a role in the early development of the kidney. May be involved in the regulation of ureteric bud initiation.
基因功能參考文獻(xiàn):
Study coupled human genetics with functional validation in zebrafish and identified IFT27 as a novel BBS gene (BBS19). PMID: 24488770