IFITM5 Antibody

中文名稱：

IFITM5兔多克隆抗體
貨號：

CSB-PA011028HA01HU
規格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA011028HA01HU at dilution of 1:100

Immunofluorescent analysis of Hela cells using CSB-PA011028HA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) IFITM5 Polyclonal antibody
Uniprot No.：

A6NNB3
基因名：

IFITM5
別名：

IFITM5; Interferon-induced transmembrane protein 5; Bone-restricted interferon-induced transmembrane protein-like protein; BRIL; Dispanin subfamily A member 1; DSPA1
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Interferon-induced transmembrane protein 5 protein (1-36AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，IFITM5 Antibody (CSB-PA011028HA01HU)，的標記方式是Non-conjugated。對于IFITM5 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA011028HB01HU	IFITM5 Antibody, HRP conjugated	ELISA
FITC	CSB-PA011028HC01HU	IFITM5 Antibody, FITC conjugated
Biotin	CSB-PA011028HD01HU	IFITM5 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC, IF

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Required for normal bone mineralization.
基因功能參考文獻：
1. Two mutations in IFITM5 causing distinct forms of osteogenesis imperfect. PMID: 24478195
2. The point mutation, c.-14C>T in the 5'-untranslated region of IFITM5, is responsible for osteogenesis imperfecta type V in Chinese patients. PMID: 23977282
3. The IFITM5 5' UTR was sequenced in 9 heterozygous subjects with osteogenesis imperfecta type V. Both wild-type and mutant IFITM5 mRNA transcripts were present in bone. Identical mutations have variable phenotypic expression, even within the same family. PMID: 24674092
4. The bone mineral density varied greatly, even within families. Our study thus highlights the phenotypic variability of OI type V caused by the IFITM5 mutation. PMID: 23408678
5. Recurrent mutation in the 5'-UTR of IFITM5 causes osteogenesis imperfecta type V. PMID: 23813632
6. IFITM5 mutation is associated with Osteogenesis imperfecta type V. PMID: 23804581
7. study demonstrates the presence of a recurrent IFITM5 mutation in a population of patients with osteogenesis imperfecta type V; even though the disease-causing mutation is identical among patients, the interindividual phenotypic variability is considerable PMID: 23240094
8. A single recurrent mutation in the 5'-UTR of IFITM5 causes osteogenesis imperfecta type V. PMID: 22863190
9. A mutation in the 5'-UTR of IFITM5 creates an in-frame start codon and causes autosomal-dominant osteogenesis imperfecta type V with hyperplastic callus. PMID: 22863195
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相關疾病：

Osteogenesis imperfecta 5 (OI5)
亞細胞定位：

Cell membrane; Multi-pass membrane protein.
蛋白家族：

CD225/Dispanin family
組織特異性：

Detected in bone. Detected in osteoblasts and fibroblasts (at protein level). Detected in bone. Detected in osteoblasts and fibroblasts.
數據庫鏈接：

HGNC: 16644

OMIM: 610967

KEGG: hsa:387733

STRING: 9606.ENSP00000372059

UniGene: Hs.443469

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