HYDIN Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) HYDIN Polyclonal antibody
Uniprot No.：

Q4G0P3
基因名：

HYDIN
別名：

CILD5 antibody; Hydin antibody; HYDIN axonemal central pair apparatus protein antibody; HYDIN_HUMAN antibody; HYDIN1 antibody; HYDIN2 antibody; Hydrocephalus-inducing protein homolog antibody; PPP1R31 antibody; Protein phosphatase 1 regulatory subunit 31 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Hydrocephalus-inducing protein homolog protein (101-400AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Required for ciliary motility.
基因功能參考文獻：
1. Three loci with high mutation frequencies, the 138665410 FOXL2 gene variant, the 23862952 MYH6 gene variant, and the 71098693 HYDIN gene variant were found to be significantly associated with sporadic Atrial Septal Defect (P<0.05); variants in FOXL2 and MYH6 were found in patients with isolated, sporadic Atrial Septal Defect (P<5x10-4). PMID: 29505555
2. The results suggest frequent and coordinated adaptive immune responses against HYDIN variants in patients with cancer. PMID: 24777681
3. We have found that the human HYDIN locus has been very recently duplicated, with a nearly identical 360-kb paralogous segment inserted on chromosome 1q21.1 PMID: 16938426
相關疾病：

Ciliary dyskinesia, primary, 5 (CILD5)
亞細胞定位：

Cell projection, cilium. Cytoplasm, cytoskeleton, cilium axoneme.
數據庫鏈接：

HGNC: 19368

OMIM: 608647

KEGG: hsa:54768

STRING: 9606.ENSP00000314736

UniGene: Hs.351914

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