HTRA4 Antibody
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中文名稱：HTRA4兔多克隆抗體
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貨號：CSB-PA010904GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：HTRA4
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別名：FLJ90724 antibody; High temperature requirement protean A4 antibody; High-temperature requirement factor A4 antibody; HTRA 4 antibody; HtrA serine peptidase 4 antibody; HTRA4 antibody; HTRA4_HUMAN antibody; Probable serine protease HTRA4 antibody; Serine protease HTRA4 antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human HTRA4
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Serine protease.
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基因功能參考文獻：
- the aberrant expression of HTRA1 or HTRA4 may be involved in the onset of preeclampsia, and increased HTRA1 or HTRA4 expression may affect trophoblast functions. PMID: 30015931
- GATA3 knockdown elevated HtrA4 expression in BeWo and JEG-3 trophoblast cell lines and enhanced the invasion activities of both lines. This study uncovered a new GATA3 function in placenta as a negative regulator of GCM1 activity and trophoblastic invasion. PMID: 26899996
- HtrA4 represents a novel placenta-specific serine protease that is altered specifically in early-onset preeclampsia with potential causal roles in endothelial dysfunction and disease development. PMID: 25946029
- Conditioned media from these two cell lines after decidualization treatment suppress HtrA4-expressing JAR cell invasion in an HtrA1- or HtrA3-dependent manner. PMID: 25002585
- Data suggest that increased HtrA4 (and HtrA1) in placenta tissues may be involved in onset of pre-eclampsia; elevated level of HtrA4 (but not HtrA1) in sera has potential as biomarker for pre-eclampsia. PMID: 22964307
- study reveals a novel function of GCM1 and HtrA4 in regulation of trophoblast invasion and that abnormal HrtA4 expression may contribute to shallow trophoblast invasion in preeclampsia PMID: 22778138
- FLJ90724 or HTRA4 is a member of the HtrA family of proteases PMID: 12408815
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亞細胞定位：Secreted.
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蛋白家族：Peptidase S1C family
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數據庫鏈接：
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