HSPA12A Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) HSPA12A Polyclonal antibody
Uniprot No.：

O43301
基因名：

HSPA12A
別名：

FLJ13874 antibody; Heat shock 70 kDa protein 12A antibody; heat shock 70kD protein 12A antibody; heat shock 70kDa protein 12A antibody; HS12A_HUMAN antibody; Hspa12a antibody; KIAA0417 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Heat shock 70 kDa protein 12A protein (2-231AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Adapter protein for SORL1, but not SORT1. Delays SORL1 internalization and affects SORL1 subcellular localization.
基因功能參考文獻：
1. The genotype "A/G" of rs1665650 in HSPA12A gene was associated with a decreased risk of gastric cancer. PMID: 26302849
2. High BCLC staging scores, advanced cirrhosis and the overexpression of HSPA12A and HSP90B1 might be associated with poor survival from HCC, whereas high levels of HSPA4, HSPA5 and HSPA6 might be associated with earlier recurrence of HCC PMID: 25798051
3. We found that HSPA12A is expressed in the human brain and shows a neuron- and region-specific transcript distribution, with strongest expression in the frontal and occipital cortical regions. HSPA12A Mrna was significantly reduced in schizophrenia. PMID: 15601604
4. Observational study of gene-disease association. (HuGE Navigator) PMID: 17601350
5. Observational study of gene-disease association. (HuGE Navigator) PMID: 18977241
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亞細胞定位：

Cytoplasm. Nucleus.
蛋白家族：

Heat shock protein 70 family
組織特異性：

Widely expressed with highest levels in brain, kidney and muscle.
數據庫鏈接：

HGNC: 19022

OMIM: 610701

KEGG: hsa:259217

STRING: 9606.ENSP00000358211

UniGene: Hs.648448

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