HSD17B11 Antibody

中文名稱：

HSD17B11兔多克隆抗體
貨號：

CSB-PA843318HA01HU
規格：

￥440
圖片：
Western blot
All lanes: HSD17B11 antibody at 10µg/ml + Mouse lung tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 33 kDa
Observed band size: 33 kDa
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) HSD17B11 Polyclonal antibody
Uniprot No.：

Q8NBQ5
基因名：

HSD17B11
別名：

17 beta HSD 11 antibody; 17 beta HSD XI antibody; 17 BETA HSD11 antibody; 17 BETA HSDXI antibody; 17 beta hydroxysteroid dehydrogenase 11 antibody; 17 beta hydroxysteroid dehydrogenase type XI antibody; 17 beta hydroxysteroid dehydrogenase XI antibody; 17-beta-HSD 11 antibody; 17-beta-HSD XI antibody; 17-beta-hydroxysteroid dehydrogenase 11 antibody; 17-beta-hydroxysteroid dehydrogenase XI antibody; 17betaHSD11 antibody; 17betaHSDXI antibody; 17bHSD11 antibody; CTCL associated antigen HD CL 03 antibody; CTCL tumor antigen HD CL 03 antibody; CTCL-associated antigen HD-CL-03 antibody; Cutaneous T cell lymphoma associated antigen HD CL 03 antibody; Cutaneous T-cell lymphoma-associated antigen HD-CL-03 antibody; Dehydrogenase/reductase SDR family member 8 antibody; DHB11_HUMAN antibody; DHRS8 antibody; Estradiol 17 beta dehydrogenase 11 antibody; Estradiol 17-beta-dehydrogenase 11 antibody; Hsd17b11 antibody; Hydroxysteroid (17 beta) dehydrogenase 11 antibody; PAN1B antibody; Retinal short chain dehydrogenase/reductase 2 antibody; Retinal short-chain dehydrogenase/reductase 2 antibody; RETSDR2 antibody; SDR16C2 antibody; SDR2 antibody; Short chain dehydrogenase/reductase family 16C member 2 antibody; T cell lymphoma associated antigen HD CL 03 antibody
宿主：

Rabbit
反應種屬：

Human, Mouse
免疫原：

Recombinant Human Estradiol 17-beta-dehydrogenase 11 protein (20-300AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，HSD17B11 Antibody (CSB-PA843318HA01HU)，的標記方式是Non-conjugated。對于HSD17B11 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA843318HB01HU	HSD17B11 Antibody, HRP conjugated	ELISA
FITC	CSB-PA843318HC01HU	HSD17B11 Antibody, FITC conjugated
Biotin	CSB-PA843318HD01HU	HSD17B11 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, WB

推薦稀釋比：

Application	Recommended Dilution
WB	1:1000-1:5000

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor-associated antigen in cutaneous T-cell lymphoma.
基因功能參考文獻：
1. knowledge of its in vitro activity together with a newly described expression pattern at the protein level in tissues involved in steroidogenesis and detoxification could suggest a potential role of DHRS8 in vivo PMID: 26472732
2. hydroxysteroid (17-beta) dehydrogenase 11 transcription in prostate cancer cells is regulated by Sp1 transcription factor and C-EBP alpha PMID: 21549806
3. Role for 17-beta-HSDXI in androgen metabolism during steroidogenesis. PMID: 12697717
4. Mutation analyses suggest that the PAT-like motif in 17betaHSD11 will not be functionally similar to the canonical PAT motif. PMID: 18804447
5. Increased Pan1b is associated with prostate cancer of seminal vesicle invasion. PMID: 19469652
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亞細胞定位：

Endoplasmic reticulum. Lipid droplet.
蛋白家族：

Short-chain dehydrogenases/reductases (SDR) family, 17-beta-HSD 3 subfamily
組織特異性：

Present at high level in steroidogenic cells such as syncytiotrophoblasts, sebaceous gland, Leydig cells, and granulosa cells of the dominant follicle and corpus luteum. In lung, it is detected in the ciliated epithelium and in acini of adult trachea, in
數據庫鏈接：

HGNC: 22960

OMIM: 612831

KEGG: hsa:51170

STRING: 9606.ENSP00000351035

UniGene: Hs.594923

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