HS6ST1 Antibody, FITC conjugated
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中文名稱：HS6ST1兔多克隆抗體, FITC偶聯(lián)
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貨號：CSB-PA010756LC01HU
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規(guī)格：￥880
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) HS6ST1 Polyclonal antibody
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Uniprot No.：
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基因名：HS6ST1
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別名：HS6ST1; HS6ST; Heparan-sulfate 6-O-sulfotransferase 1; HS6ST-1
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Heparan-sulfate 6-O-sulfotransferase 1 protein (3-133AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：FITC
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產(chǎn)品提供形式：Liquid
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
相關產(chǎn)品
靶點詳情
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功能：6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. Critical for normal neuronal development where it may play a role in neuron branching. May also play a role in limb development. May prefer iduronic acid.
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基因功能參考文獻：
- RT-PCR analysis showed that the overall transcriptional activity of the main Heparan Sulfate biosynthesis-involved genes (EXT1, EXT2, NDST1, NDST2, GLCE, HS2ST1, HS3ST1, HS3ST2, HS6ST1, HS6ST2, SULF1, SULF2, HPSE) was decreased by 1.5-2-fold in Grade II-III glioma. PMID: 29104277
- HS6ST-1 and HS6ST-2 have roles in regulating the angiogenic program in ovarian cancer cells affecting HB-EGF signaling and subsequent expression of angiogenic cytokines by cancer cells PMID: 24563483
- Hs6st1 and Hs2st generate conditions conducive to corpus callosum development. PMID: 24501377
- idiopathic hypogonadotrophic hypogonadism--associated HS6ST1 mutations display reduced activity in vitro and in vivo, suggesting that HS6ST1 and the complex modifications of extracellular sugars are critical for normal development PMID: 21700882
- we have characterized HS6ST-2 and HS6ST-1 human isologues, including their chromosomal localizations,HS6STs could also transfer sulphate to N -sulphoglucosamine residues located at the non-reducing terminal of HS with high affinity. PMID: 12492399
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相關疾病：Hypogonadotropic hypogonadism 15 with or without anosmia (HH15)
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亞細胞定位：Membrane; Single-pass type II membrane protein.
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蛋白家族：Sulfotransferase 6 family
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組織特異性：Expressed in fetal brain.
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數(shù)據(jù)庫鏈接：
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