HPD Antibody
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中文名稱(chēng)：HPD兔多克隆抗體
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貨號(hào)：CSB-PA010698LA01HU
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規(guī)格：￥440
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圖片：
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Western blot
All lanes: HPD antibody at 4.5µg/ml
Lane 1: Mouse kidney tissue
Lane 2: Mouse liver tissue
Lane 3: HepG2 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 45, 41 kDa
Observed band size: 45 kDa -
Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA010698LA01HU at dilution of 1:20 -
Immunofluorescent analysis of HepG2 cells using CSB-PA010698LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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其他：
產(chǎn)品詳情
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產(chǎn)品描述：
Inoculating a rabbit with recombinant human 4-hydroxyphenylpyruvate dioxygenase protein (2-393aa), extracting antibodies from the rabbit serum, and then purifying the collected antibodies via protein G affinity chromatography. The resulting antibody is the HPD polyclonal antibody. It contains minimal impurities, and its purity exceeds 95%.
This HPD polyclonal is capable of recognizing and binding to HPD protein from human and mouse samples. It has been validated in various experimental settings, including ELISA, WB, IHC, and IF, and can be used for the detection of levels, determination of presence and size, and analysis of the distribution of the HPD protein.
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產(chǎn)品名稱(chēng)：Rabbit anti-Homo sapiens (Human) HPD Polyclonal antibody
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Uniprot No.：
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基因名：HPD
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別名：4 HPPD antibody; 4 hydroxyphenylpyruvate dioxygenase antibody; 4 hydroxyphenylpyruvic acid oxidase antibody; 4-hydroxyphenylpyruvate dioxygenase antibody; 4-hydroxyphenylpyruvic acid oxidase antibody; 4HPPD antibody; GLOD3 antibody; glyoxalase domain containing 3 antibody; HPD antibody; HPPD_HUMAN antibody; HPPDase antibody; PPD antibody
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宿主：Rabbit
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反應(yīng)種屬：Human, Mouse
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免疫原：Recombinant Human 4-hydroxyphenylpyruvate dioxygenase protein (2-393AA)
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：Non-conjugated
本頁(yè)面中的產(chǎn)品，HPD Antibody (CSB-PA010698LA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于HPD Antibody，我們還提供其他標(biāo)記。見(jiàn)下表：
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克隆類(lèi)型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA, WB, IHC, IF
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:2000 IHC 1:10-1:100 IF 1:50-1:200 -
Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Key enzyme in the degradation of tyrosine.
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基因功能參考文獻(xiàn)：
- The mutagenesis and structural simulation studies demonstrate the critical and unique role of each ligand in the function of HPPD, and which correlates with their respective co-ordination position. PMID: 26936969
- 4-hydroxyphenylpyruvate dioxygenase gene mutation is associated with Hawkinsinuria. PMID: 26226126
- Glutamine375 has a critical role for 4-HPPD in orientating the tail and ensuring the conformation of the terminal alpha-helix of the enzyme to maintain the integrity of the active site for biocatalysis. PMID: 23950902
- The IIe335Met allele is equivalent to a null mutation while the Asn241Ser allele results in a partially active enzyme with an uncoupled turnover causing elevated haykinin in urine. PMID: 17560158
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相關(guān)疾病：Tyrosinemia 3 (TYRSN3); Hawkinsinuria (HAWK)
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蛋白家族：4HPPD family
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數(shù)據(jù)庫(kù)鏈接：
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