HEXIM2 Antibody, HRP conjugated

說明書

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) HEXIM2 Polyclonal antibody
Uniprot No.：

Q96MH2
基因名：

HEXIM2
別名：

Hexamethylene bis-acetamide-inducible protein 2 antibody; Hexamthylene bis-acetamide inducible 2 antibody; HEXI2_HUMAN antibody; hexim 2 antibody; HEXIM2 antibody; L3 antibody; Protein HEXIM2 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human Protein HEXIM2 protein (1-286AA)
免疫原種屬：

Homo sapiens (Human)
標(biāo)記方式：

HRP
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA
Protocols：

ELISA Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. Core component of the 7SK RNP complex: in cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.
基因功能參考文獻(xiàn)：
1. HEXIM2 can functionally and quantitatively compensate for the loss of HEXIM1 PMID: 15713661
2. utilization of HEXIM1 or HEXIM2 to bind and inhibit P-TEFb can be differentially regulated in vivo. PMID: 15713662
3. Positive transcription elongation factor b regulates eukaryotic gene expression at the level of elongation and is controlled by the reversible association with HEXIM2. PMID: 15965233
4. The tripartite protein-RNA complex formation between Hexim, Cyclin T and 7SK snRNA, was analyzed. PMID: 19883659
亞細(xì)胞定位：

Nucleus.
蛋白家族：

HEXIM family
組織特異性：

Ubiquitously expressed with higher expression in testis. HEXIM1 and HEXIM2 are differentially expressed.
數(shù)據(jù)庫(kù)鏈接：

HGNC: 28591

OMIM: 615695

KEGG: hsa:124790

STRING: 9606.ENSP00000302276

UniGene: Hs.56382

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