HECTD3 Antibody, Biotin conjugated
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中文名稱：HECTD3兔多克隆抗體, Biotin偶聯(lián)
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貨號：CSB-PA725567LD01HU
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規(guī)格：￥880
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) HECTD3 Polyclonal antibody
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Uniprot No.：
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基因名：HECTD3
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別名：E3 ubiquitin-protein ligase HECTD3 antibody; HECD3_HUMAN antibody; HECT antibody; HECT domain containing protein 3 antibody; HECT domain-containing protein 3 antibody; HECTD3 antibody; Probable E3 ubiquitin protein ligase HECTD3 antibody
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Recombinant Human E3 ubiquitin-protein ligase HECTD3 protein (682-785AA)
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：Biotin
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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靶點詳情
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功能：E3 ubiquitin ligases accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of TRIOBP and its subsequent proteasomal degradation, thus facilitating cell cycle progression by regulating the turn-over of TRIOBP. Mediates also ubiquitination of STX8.
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基因功能參考文獻：
- HECTD3 as a tumor suppressor modulating the activity of this important oncogenic signaling pathway. PMID: 28636940
- Overexpression of MALT1 partially rescues HECTD3 depletion-induced apoptosis. PMID: 23358872
- All these findings suggest that HECTD3 may facilitate cell cycle progression via regulating ubiquitination and degradation of Tara. PMID: 18194665
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亞細胞定位：Cytoplasm, perinuclear region.
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數(shù)據(jù)庫鏈接：
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