HEBP2 Antibody

說明書

產(chǎn)品詳情

Uniprot No.：

Q9Y5Z4
基因名：

HEBP2
別名：

C6orf34 antibody; Chromosome 6 open reading frame 34 antibody; Hebp2 antibody; HEBP2_HUMAN antibody; Heme binding protein 2 antibody; Heme-binding protein 2 antibody; Placental protein 23 antibody; PP23 antibody; Protein SOUL antibody; SOUL antibody
宿主：

Rabbit
反應(yīng)種屬：

Human,Mouse,Rat
免疫原：

Human HEBP2
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Can promote mitochondrial permeability transition and facilitate necrotic cell death under different types of stress conditions.
基因功能參考文獻(xiàn)：
1. There are important structural differences in the BH3 domain in the intact SOUL molecule and the same sequence bound to Bcl-xL. PMID: 21639858
2. SOUL can be a novel member of the BH3 domain-only proteins that cannot induce cell death alone but can facilitate both outer and inner mitochondrial membrane permeabilization and predominantly necrotic cell death in oxidative stress. PMID: 19901022
3. SOUL promotes necrotic cell death by inducing mitochondrial permeability transition PMID: 17098234
4. preliminary X ray structure PMID: 19574650
亞細(xì)胞定位：

Cytoplasm. Mitochondrion.
蛋白家族：

HEBP family
組織特異性：

Detected in placenta.
數(shù)據(jù)庫鏈接：

HGNC: 15716

OMIM: 605825

KEGG: hsa:23593

STRING: 9606.ENSP00000058691

UniGene: Hs.486589

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