HAGH Antibody
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中文名稱：HAGH兔多克隆抗體
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貨號(hào)：CSB-PA11195A0Rb
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規(guī)格：￥440
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圖片：
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Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA11195A0Rb at dilution of 1:100
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) HAGH Polyclonal antibody
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Uniprot No.：
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基因名：
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別名：HAGH antibody; GLO2 antibody; HAGH1Hydroxyacylglutathione hydrolase antibody; mitochondrial antibody; EC 3.1.2.6 antibody; Glyoxalase II antibody; Glx II antibody
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Recombinant Human Hydroxyacylglutathione hydrolase, mitochondrial protein (50-308AA)
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：Non-conjugated
本頁(yè)面中的產(chǎn)品，HAGH Antibody (CSB-PA11195A0Rb)，的標(biāo)記方式是Non-conjugated。對(duì)于HAGH Antibody，我們還提供其他標(biāo)記。見(jiàn)下表：
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA, IHC
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推薦稀釋比：
Application Recommended Dilution IHC 1:20-1:200 -
Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
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基因功能參考文獻(xiàn)：
- Down regulation of Glyoxalase II was observed in cases of diabetic retinopathy as compared to controls. PMID: 29950256
- The critical role of glyoxalases as regulators of tumorigenesis in the prostate through modulation of various critical signaling pathways, and an overview of the current knowledge on glyoxalases in bladder, kidney and testis cancers is reviewed. (GLO1, GLO2) PMID: 29385039
- epidermal expression stronger in older skin donors PMID: 26914966
- Glo2, together with Glo1, represents a novel mechanism in prostate cancer progression as part of a pathway driven by PTEN/PI3K/AKT/mTOR signaling. PMID: 27696457
- This article reports for the first time a possible additional role of Glo2 that, after interacting with a target protein, is able to promote S-glutathionylation. PMID: 27935136
- This study suggested that HAGH, rs11859266 and rs3743852 showed significant associations with schizophrenia in males at allelic and genotype levels. PMID: 25645869
- No association between genetic variants of the HAGH gene and autism spectrum disorder was found. PMID: 24671236
- hydroxyacylglutathione hydrolase (HAGH) gene encodes both cytosolic and mitochondrial forms of glyoxalase II PMID: 15117945
- Overexpression of glyoxalase II is associated with kidney tumor PMID: 16803681
- Data show that the GLX2 gene, which encodes glyoxalase II enzyme, is up-regulated by p63 and p73. PMID: 16831876
- In androgen-dependent prostate cancer cells, testosterone upregulates GLO2 mRNA levels. In androgen-independent prostate cancer cells, it downregulates GLO2 mRNA. PMID: 18344682
- Human glyoxalase II contains an Fe(II)Zn(II) center but is active as a mononuclear Zn(II) enzyme PMID: 19413286
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亞細(xì)胞定位：[Isoform 1]: Mitochondrion matrix.; [Isoform 2]: Cytoplasm.
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蛋白家族：Metallo-beta-lactamase superfamily, Glyoxalase II family
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組織特異性：Expressed in liver and kidney.
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數(shù)據(jù)庫(kù)鏈接：
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