GRAP Antibody

中文名稱：

GRAP兔多克隆抗體
貨號：

CSB-PA618789LA01HU
規(guī)格：

￥440
圖片：
IHC image of CSB-PA618789LA01HU diluted at 1:30 and staining in paraffin-embedded human skeletal muscle tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
其他：

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) GRAP Polyclonal antibody
Uniprot No.：

Q13588
基因名：

GRAP
別名：

Grap antibody; GRAP_HUMAN antibody; GRB2 related adaptor protein antibody; GRB2-related adapter protein antibody; Growth factor receptor bound protein 2 related adaptor protein antibody; MGC64880 antibody; OTTHUMP00000065766 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human GRB2-related adapter protein (1-217AA)
免疫原種屬：

Homo sapiens (Human)

標(biāo)記方式：

Non-conjugated

本頁面中的產(chǎn)品，GRAP Antibody (CSB-PA618789LA01HU)，的標(biāo)記方式是Non-conjugated。對于GRAP Antibody，我們還提供其他標(biāo)記。見下表：

標(biāo)記方式	貨號	產(chǎn)品名稱	應(yīng)用
HRP	CSB-PA618789LB01HU	GRAP Antibody, HRP conjugated	ELISA
FITC	CSB-PA618789LC01HU	GRAP Antibody, FITC conjugated
Biotin	CSB-PA618789LD01HU	GRAP Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway. Plays a role in the inner ear and in hearing.
基因功能參考文獻(xiàn)：
1. Findings suggest that the miR-654-5p/GRAP/Ras/Erk signaling pathway in OSCC cells might contribute to the underlying mechanism through which miR-654-5p participates in the regulation of OSCC progression. PMID: 29364705
2. Grb2-related adaptor protein (GRAP) was up-regulated in kidney tubules from fibrotic kidneys from diabetic patients, and subsequently confirmed as a novel component of TGF-beta signaling in cultured human renal tubule cells. PMID: 19836472
3. Results suggest that the GRAP gene might have a role in the pathogenesis of Sjogren's syndrome. PMID: 15174222
4. Our findings define a pathway involving CD28 binding to Grb-2 and its co-operativity with Vav1 in the regulation of T-cell co-stimulation. PMID: 18295596
亞細(xì)胞定位：

Membrane; Peripheral membrane protein. Cell junction, synapse.
蛋白家族：

GRB2/sem-5/DRK family
數(shù)據(jù)庫鏈接：

HGNC: 4562

OMIM: 604330

KEGG: hsa:10750

STRING: 9606.ENSP00000284154

UniGene: Hs.567416

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