Western Blot
Positive WB detected in: Mouse brain tissue
All lanes: GRAMD4 antibody at 3.4µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 67, 11 kDa
Observed band size: 67 kDa
Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA764225LA01HU at dilution of 1:100
Western Blot
Positive WB detected in: MCF-7 whole cell lysate
All lanes: GRAMD4 antibody at 5µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 67, 11 kDa
Observed band size: 67 kDa
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期:
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Plays a role as a mediator of E2F1-induced apoptosis in the absence of p53/TP53. Plays a role as a mediator of E2F1-induced apoptosis in the absence of p53/TP53. Inhibits TLR9 response to nucelic acids and regulates TLR9-mediated innate immune response.
基因功能參考文獻:
The expression of GRAMD4 is up-regulated in hepatocellular carcinoma cell(HCC cell) lines and HCC tissues, and the increased expression is correlated with the clinicopathological characteristics of HCC. PMID: 23388340
GRAMD4 induces changes in Bcl-2 and Bax protein levels PMID: 21127500
localizes to the mitochondria, upregulated following E2F1 induction PMID: 15565177
DIP induces p53-independent caspase-dependent and -independent apoptosis. DIP is localized in the mitochondria. DIP accumulates upon E2F1 activation. PMID: 15565177