GPR50 Antibody
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中文名稱：GPR50兔多克隆抗體
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貨號：CSB-PA002780
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規(guī)格：￥1090
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圖片：
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Western Blot analysis of A549 cells using GPR50 Polyclonal Antibody
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：
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別名：GPR50; Melatonin-related receptor; G protein-coupled receptor 50; H9
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Synthesized peptide derived from the Internal region of Human GPR50.
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：WB, IF, ELISA
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:2000 IF 1:200-1:1000 ELISA 1:10000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Does not bind melatonin.
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基因功能參考文獻(xiàn)：
- GPR50 is a TbetaRI co-receptor with potential impact on cancer development PMID: 29572483
- Pre-eclampsia (PE) plasma IgG1 anti-Epstein-Barr virus nuclear antigen 1 (EBNA-1) antibody cross-reacts with placental protein G protein-coupled receptor 50 (GPR50). PMID: 27181993
- The results provide deeper insight into the functional evolution of GPR50 in mammals at the molecular level PMID: 25730005
- There was only weak female-specific association between GPR50 variants in late-life depression. No significant associations were observed in men. PMID: 25798330
- study found an association between Seasonal Affective Disorder (SAD) and a single nucleotide polymorphism (intronic rs2072621) of the gene encoding GPR50 in females. PMID: 21565467
- Positive expression of melatonin receptor can be found in human hypertrophic scar and normal skin, but it is higher in scar. PMID: 20737950
- we found 2 polymorphisms in the GPR50 receptor of patients with adolescent idiopathic scoliosis, but they were not present at a highly significant frequency when compared with controls PMID: 20733416
- Antibodies were used to study the expression of GPR50 in mouse, rat and human hypothalamus.GPR50 immunoreactivity (ir) was observed in dorsomedial hypothalamic (DMH) cells and in cells of the ependymal layer of the third ventricle of the hypothalamus. PMID: 20210849
- This is the first association of rs1202874 with BD and is the second positive association at the GPR50 locus. PMID: 20371266
- Results identify neurite outgrowth inhibitor NOGO-A as an interacting partner of GPR50 and found an enrichment of both Gpr50 and neuronal Nogo-A at the synapse. PMID: 19699797
- Polymorphisms in GPR50 were compared in bipolar affective disorder (BD), major depressive disorder (MDD), schizophrenia (SCZ) and controls. GPR50(Delta502-505) or a variant is a sex-specific risk factor for susceptibility to BD and SCZ. PMID: 15452587
- Results describe sequence variants in the melatonin-related receptor gene (GPR50) that associate with circulating triglyceride and HDL levels. PMID: 16436372
- GPR50, an orphan GPCR, heterodimerizes constitutively and specifically with MT(1) and MT(2) melatonin receptors PMID: 16778767
- No evidence for an association for this gene with mood disorders in a Hungarian population. PMID: 18075476
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亞細(xì)胞定位：Cell membrane; Multi-pass membrane protein.
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蛋白家族：G-protein coupled receptor 1 family
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組織特異性：Hypothalamus and pituitary.
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數(shù)據(jù)庫鏈接：
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